[HTML][HTML] Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling
A Płóciennikowska, A Hromada-Judycka… - Cellular and molecular …, 2015 - Springer
Abstract Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), a component of
Gram-negative bacteria to induce production of pro-inflammatory mediators aiming at …
Gram-negative bacteria to induce production of pro-inflammatory mediators aiming at …
[HTML][HTML] TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
A Ciesielska, M Matyjek, K Kwiatkowska - Cellular and molecular life …, 2021 - Springer
Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …
Exploring the LPS/TLR4 signal pathway with small molecules
F Peri, M Piazza, V Calabrese… - Biochemical Society …, 2010 - portlandpress.com
The identification of the bacterial endotoxin receptors for innate immunity, most notably
TLR4 (Toll-like receptor 4), has sparked great interest in therapeutic manipulation of the …
TLR4 (Toll-like receptor 4), has sparked great interest in therapeutic manipulation of the …
LPS/TLR4 signal transduction pathway
The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the
release of critical proinflammatory cytokines that are necessary to activate potent immune …
release of critical proinflammatory cytokines that are necessary to activate potent immune …
The role of toll‐like receptor 4 in infectious and noninfectious inflammation
M Molteni, S Gemma, C Rossetti - Mediators of inflammation, 2016 - Wiley Online Library
Toll‐like receptor 4 (TLR4) belongs to the family of pattern recognition receptors (PRRs).
They are highly conserved receptors that recognize conserved pathogen‐associated …
They are highly conserved receptors that recognize conserved pathogen‐associated …
MD-2: the Toll 'gatekeeper'in endotoxin signalling
M Gangloff, NJ Gay - Trends in biochemical sciences, 2004 - cell.com
Lipopolysaccharide (LPS) from the outer cell wall of Gram-negative bacteria is a potent
stimulator of the mammalian innate immune system. The Toll-like receptor 4 (TLR4) pathway …
stimulator of the mammalian innate immune system. The Toll-like receptor 4 (TLR4) pathway …
[HTML][HTML] The role of carbohydrates in the lipopolysaccharide (LPS)/toll-like receptor 4 (TLR4) signalling
F Cochet, F Peri - International journal of molecular sciences, 2017 - mdpi.com
The interactions between sugar-containing molecules from the bacteria cell wall and pattern
recognition receptors (PRR) on the plasma membrane or cytosol of specialized host cells …
recognition receptors (PRR) on the plasma membrane or cytosol of specialized host cells …
TLR signaling pathway in patients with sepsis
The pathogenesis of sepsis involves complex interaction between the host and the infecting
microorganism. Bacterial recognition and signaling are essential functions of the cells of …
microorganism. Bacterial recognition and signaling are essential functions of the cells of …
[HTML][HTML] Lipopolysaccharide recognition in the crossroads of TLR4 and caspase-4/11 mediated inflammatory pathways
A Zamyatina, H Heine - Frontiers in Immunology, 2020 - frontiersin.org
The innate immune response to lipopolysaccharide is essential for host defense against
Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is …
Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is …
The molecular basis of the host response to lipopolysaccharide
Lipopolysaccharide (LPS), which is produced by Gram-negative bacteria, is a powerful
activator of innate immune responses. LPS binds to the proteins Toll-like receptor 4 (TLR4) …
activator of innate immune responses. LPS binds to the proteins Toll-like receptor 4 (TLR4) …