[HTML][HTML] Blood-brain barrier, blood-brain tumor barrier, and fluorescence-guided neurosurgical oncology: delivering optical labels to brain tumors

E Belykh, KV Shaffer, C Lin, VA Byvaltsev… - Frontiers in …, 2020 - frontiersin.org
Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Optical principles of fluorescence-guided brain tumor surgery: a practical primer for the neurosurgeon

DY Zhang, S Singhal, JYK Lee - Neurosurgery, 2019 - journals.lww.com
Fluorescence-guided surgery is a rapidly growing field that has produced some of the most
important innovations in surgical oncology in the past decade. These intraoperative imaging …

[HTML][HTML] Indocyanine-green for fluorescence-guided surgery of brain tumors: evidence, techniques, and practical experience

SS Cho, R Salinas, JYK Lee - Frontiers in surgery, 2019 - frontiersin.org
The primary treatment for brain tumors often involves surgical resection for diagnosis, relief
of mass effect, and prolonged survival. In neurosurgery, it is of utmost importance to achieve …

[HTML][HTML] Intraoperative fluorescence imaging for personalized brain tumor resection: current state and future directions

E Belykh, NL Martirosyan, K Yagmurlu, EJ Miller… - Frontiers in …, 2016 - frontiersin.org
Introduction Fluorescence-guided surgery is one of the rapidly emerging methods of surgical
“theranostics.” In this review, we summarize current fluorescence techniques used in …

[HTML][HTML] Fluorescence-guided surgery: a review on timing and use in brain tumor surgery

AJ Schupper, M Rao, N Mohammadi, R Baron… - Frontiers in …, 2021 - frontiersin.org
Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …

[HTML][HTML] Fluorescence-guided surgery in the surgical treatment of gliomas: Past, present and future

R Sun, H Cuthbert, C Watts - Cancers, 2021 - mdpi.com
Simple Summary Gliomas are aggressive central nervous system tumours. The emergence
and recent widespread adoption of 5-aminolevulinic acid and fluorescence guided surgery …

What is the surgical benefit of utilizing 5-aminolevulinic acid for fluorescence-guided surgery of malignant gliomas?

CG Hadjipanayis, G Widhalm, W Stummer - Neurosurgery, 2015 - journals.lww.com
The current neurosurgical goal for patients with malignant gliomas is maximal safe resection
of the contrast-enhancing tumor. However, a complete resection of the contrast-enhancing …

Trends in fluorescence image-guided surgery for gliomas

JTC Liu, D Meza, N Sanai - Neurosurgery, 2014 - journals.lww.com
Mounting evidence suggests that a more extensive surgical resection is associated with an
improved life expectancy for both low-grade and high-grade glioma patients. However …

[HTML][HTML] Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results

JT Senders, IS Muskens, R Schnoor, AV Karhade… - Acta …, 2017 - Springer
Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …

Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies

Y Li, R Rey-Dios, DW Roberts, PA Valdés… - World neurosurgery, 2014 - Elsevier
Objective Fluorescence guidance has a demonstrated potential in maximizing the extent of
high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5 …