Clinical xenotransplantation: the next medical revolution?

B Ekser, M Ezzelarab, H Hara, DJ van der Windt… - The lancet, 2012 - thelancet.com
The shortage of organs and cells from deceased individuals continues to restrict
allotransplantation. Pigs could provide an alternative source of tissue and cells but the …

Clinical xenotransplantation of solid organs

A Dorling, K Riesbeck, A Warrens, R Lechler - The Lancet, 1997 - thelancet.com
A possible solution to the chronic shortage of allografts is xenotransplantation, the use of
tissue from an animal donor. Most experts believe that the pig will provide the most suitable …

Next steps for the xenotransplantation of pig organs into humans

RA Montgomery, SA Mehta, B Parent, A Griesemer - Nature Medicine, 2022 - nature.com
Next steps for the xenotransplantation of pig organs into humans | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

[HTML][HTML] Xenotransplantation—the current status and prospects

DKC Cooper, R Gaston, D Eckhoff… - British medical …, 2018 - ncbi.nlm.nih.gov
Introduction: There is a continuing worldwide shortage of organs from deceased human
donors for transplantation into patients with end-stage organ failure. Genetically engineered …

[PDF][PDF] The generation of transgenic pigs as potential organ donors for humans

E Cozzi, DJG White - Nature medicine, 1995 - researchgate.net
Success of transplantation as a therapeutic option in terminal organ failure has resulted in
the widespread diffusion of this life-saving treatmet and a consequent worldwide organ …

Pig-to-human heart xenotransplantation in two recently deceased human recipients

N Moazami, JM Stern, K Khalil, JI Kim, N Narula… - Nature medicine, 2023 - nature.com
Genetically modified xenografts are one of the most promising solutions to the discrepancy
between the numbers of available human organs for transplantation and potential recipients …

Overcoming the barriers to xenotransplantation: prospects for the future

B Ekser, DKC Cooper - Expert review of clinical immunology, 2010 - Taylor & Francis
Cross-species transplantation (xenotransplantation) has immense potential to solve the
critical need for organs, tissues and cells for clinical transplantation. The increasing …

[PDF][PDF] Uncertainty in xenotransplantation: individual benefit versus collective risk

FH Bach, JA Fishman, N Daniels, J Proimos… - Nature …, 1998 - academia.edu
Clinical xenotransplantation, the transplantation of cells, tissues or organs from non-humans
to humans, crosses a species barrier that has evolved over millions of years. In doing so, it …

Pig kidney xenotransplantation: progress toward clinical trials

DKC Cooper, H Hara, H Iwase… - Clinical …, 2021 - Wiley Online Library
Pig organ xenotransplantation offers a solution to the shortage of deceased human organs
for transplantation. The pathobiological response to a pig xenograft is complex, involving …

Regulation of clinical xenotransplantation—time for a reappraisal

DKC Cooper, RN Pierson III, BJ Hering… - …, 2017 - journals.lww.com
The continual critical shortage of organs and cells from deceased human donors has
stimulated research in the field of cross-species transplantation (xenotransplantation), with …