Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

Once thought to be exclusively a storage hub for glucose, glycogen is now known to be
essential in a range of physiological processes and pathological conditions. Glycogen lies at …

Cancer is a disease at the cellular level involving heritable disorders in cellular control
mechanism. Cancer cells also need to adapt their metabolism to survive and multiply under …

Aerobic glycolysis is the process of oxidation of glucose into pyruvate followed by lactate
production under normoxic condition. Distinctive from its anaerobic counterpart (ie glycolysis …

Metabolic reprogramming of cancer cells provides energy and multiple intermediates critical
for cell growth. Hypoxia in tumors represents a hostile environment that can encourage …

It is well known that tumor cells rely mainly on aerobic glycolysis for energy production even
in the presence of oxygen, and glycolysis is a known modulator of tumorigenesis and tumor …

Cancer cells reprogram their metabolism to meet the requirement for survival and rapid
growth. One hallmark of cancer metabolism is elevated aerobic glycolysis and reduced …

Since its identification more than 150 years ago, there has been an extensive
characterisation of glycogen metabolism and its regulatory pathways in the two main …

Altered energy metabolism is a biochemical fingerprint of cancer cells that represents one of
the “hallmarks of cancer”. This metabolic phenotype is characterized by preferential …

Cancer is the second most important cause of death and new therapy modalities continue to
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …