Background The circulating form of human endoglin (sEng) is a cleavage product of
membrane-bound endoglin present on endothelial cells. Because sEng encompasses an …

Complex interactions between platelets and activated endothelium occur during the thrombo-
inflammatory reaction at sites of vascular injuries and during vascular hemostasis. The …

Endoglin, alias CD105, is a human membrane glycoprotein highly expressed in vascular
endothelial cells. It is involved in angiogenesis and angiogenesis-related diseases …

The circulatory system is walled off by different cell types, including vascular mural cells and
podocytes. The interaction and interplay between endothelial cells (ECs) and mural cells …

Endoglin (ENG) is a transmembrane glycoprotein expressed on endothelial cells that
functions as a co-receptor for several ligands of the transforming growth factor beta (TGF-β) …

Aims Endoglin is a transmembrane glycoprotein, that plays an important role in regulating
endothelium. Proteolytic cleavage of membrane endoglin releases soluble endoglin (sEng) …

Increased levels of a soluble form of endoglin (sEng) circulating in plasma have been
detected in various pathological conditions related to cardiovascular system. High …

Human endoglin is an RGD-containing transmembrane glycoprotein identified in vascular
endothelial cells. Although endoglin is essential for angiogenesis and its expression is up …

Objective—Transforming growth factor-β inhibits migration and proliferation of endothelial
and smooth muscle cells. Endoglin is a transmembrane receptor for transforming growth …

Introduction The applicability of protein drugs is confined by protein degradation and rapid
elimination. PEGylation of polypeptides improves protein stability by sterically obstructing …