[HTML][HTML] Improved bladder contractility after transplantation of human mesenchymal stem cells overexpressing hepatocyte growth factor into underactive bladder from …

JH Kim, HJ Yang, SS Choi, SU Kim, HJ Lee, YS Song - Plos one, 2021 - journals.plos.org
Introduction An underactive bladder can lead to difficulty in voiding that causes incomplete
emptying of the bladder, suggesting the need for a new strategy to increase bladder …

Mesenchymal stem cells overexpressing hepatocyte growth factor (HGF) inhibit collagen deposit and improve bladder function in rat model of bladder outlet …

YS Song, HJ Lee, SH Doo, SJ Lee, I Lim… - Cell …, 2012 - journals.sagepub.com
Bladder outlet obstruction (BOO) caused by collagen deposit is one of the most common
problems in elderly male. This study was performed to examine the capability of human …

[HTML][HTML] Benefits of mesenchymal stem cells after partial bladder outlet obstruction

B Al-Saikan, J Ding, E Tredget… - Canadian Urological …, 2016 - ncbi.nlm.nih.gov
Methods: After University ethics approval, 5× 106 green fluorescent protein GFP-labeled
MSC were intravenously injected concurrently with pBOO in adult Sprague-Dawley rats. Five …

[HTML][HTML] A preclinical study of human embryonic stem cell-derived mesenchymal stem cells for treating detrusor underactivity by chronic bladder ischemia

HY Yu, JH Shin, HD Yun, CM Ryu, S Lee, J Heo… - Stem cell reviews and …, 2021 - Springer
Background The therapeutic effects of human embryonic stem cell-derived multipotent
mesenchymal stem cells (M-MSCs) were evaluated for detrusor underactivity (DUA) in a rat …

Mesenchymal stem cell recruitment and improved bladder function after bladder outlet obstruction: preliminary data

LL Woo, ST Tanaka, G Anumanthan, JC Pope… - The Journal of …, 2011 - auajournals.org
Purpose: Mesenchymal stem cells have various therapeutic benefits in various organ injury
models. Bladder outlet obstruction causes smooth muscle hypertrophy and fibrosis, leading …

Contribution of bone marrow‐derived mesenchymal stem cells to the morphological changes in the bladder after partial outlet obstruction: A preliminary study

Y Kanno, T Mitsui, H Sano, T Kitta… - … Journal of Urology, 2014 - Wiley Online Library
Objectives To investigate the contribution of bone marrow‐derived mesenchymal stem cells
to the changes in bladder morphology in response to partial bladder outlet obstruction …

Inhibition of collagen deposit in obstructed rat bladder outlet by transplantation of superparamagnetic iron oxide-labeled human mesenchymal stem cells as monitored …

HJ Lee, JH Won, SH Doo, JH Kim… - Cell …, 2012 - journals.sagepub.com
Bladder outlet obstruction (BOO) caused by collagen deposit is one of the most common
problems in elderly males. The present study is to investigate if human mesenchymal stem …

Intraperitoneal administration of mesenchymal stem cells is effective at mitigating detrusor deterioration after pBOO

B Wiafe, R Kadam, PD Metcalfe - American Journal of …, 2020 - journals.physiology.org
Partial bladder outlet obstruction (pBOO) results in bladder fibrosis that is initiated by an
inflammatory cascade and the decompensation after smooth muscle hypertrophy. We have …

Mesenchymal stem cells inhibit hypoxia-induced inflammatory and fibrotic pathways in bladder smooth muscle cells

B Wiafe, A Adesida, T Churchill, P Metcalfe - World Journal of Urology, 2018 - Springer
Purpose Partial bladder outlet obstruction is a multifactorial urological condition in which
hypoxia plays a significant role. We recently investigated hypoxia's role as a single stressor …

Mesenchymal stem cell therapy inhibited inflammatory and profibrotic pathways induced by partial bladder outlet obstruction and prevented high-pressure urine …

B Wiafe, AB Adesida, T Churchill, R Kadam… - Journal of Pediatric …, 2019 - Elsevier
Background Partial bladder outlet obstruction (pBOO) is characterized by an initial
inflammatory response that progresses to smooth muscle hypertrophy and fibrosis. Current …