Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease?

M Huttasch, M Roden, S Kahl - Metabolism, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD) closely associates with
obesity and type 2 diabetes. Lifestyle intervention and bariatric surgery aiming at substantial …

Effect of weight loss medications on hepatic steatosis and steatohepatitis: a systematic review

CS Pan, TL Stanley - Frontiers in Endocrinology, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a common comorbidity in individuals with
obesity. Although multiple pharmacotherapeutics are in development, currently there are …

Role of lifestyle and glucagon‐like peptide‐1 receptor agonists for weight loss in obesity, type 2 diabetes and steatotic liver diseases

A Giannakogeorgou, M Roden - Alimentary Pharmacology & …, 2024 - Wiley Online Library
Background The current obesity pandemic has given rise to associated comorbidities and
complications, including type 2 diabetes and metabolic dysfunction‐associated steatotic …

The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic-Dysfunction Associated Steatohepatitis

LA Abushamat, PA Shah, RH Eckel, SA Harrison… - Clinical …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one in three to four
adult individuals and can progress to metabolic dysfunction-associated steatohepatitis …

SGLT-2 inhibitors and GLP-1 receptor agonists in metabolic dysfunction-associated fatty liver disease

JS Moon, JH Hong, YJ Jung, E Ferrannini… - Trends in Endocrinology …, 2022 - cell.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic condition that
affects nearly one billion people globally, characterized by triacylglycerol accumulation in …

[HTML][HTML] Emerging therapies for MASLD and their impact on plasma lipids

M Nguyen, A Asgharpour, DL Dixon, AJ Sanyal… - American Journal of …, 2024 - Elsevier
Metabolic-dysfunction associated steatotic liver disease (MASLD) affects 1 out of every 3
individuals in the adult population and the disease prevalence is predicted to increase …

Resmetirom, the first approved drug for the management of metabolic dysfunction-associated steatohepatitis: trials, opportunities, and challenges

M Kokkorakis, C Boutari, MA Hill… - Metabolism …, 2024 - metabolismjournal.com
Over the past decade, there have been several guideline updates for the diagnosis and
management of non-alcoholic fatty liver disease (NAFLD), which is the most common …

[HTML][HTML] EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

F Tacke, P Horn, VWS Wong, V Ratziu, E Bugianesi… - Journal of …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-
alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the …

The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis

MP Cooreman, J Butler, RP Giugliano… - Nature …, 2024 - nature.com
Lanifibranor, a pan-PPAR agonist, improves liver histology in patients with metabolic
dysfunction-associated steatohepatitis (MASH), who have poor cardiometabolic health …

What is new in metabolic dysfunction-associated Steatotic liver disease in lean individuals: from bench to bedside

P Danpanichkul, K Suparan, D Kim… - Journal of Clinical …, 2024 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects more than 30% of
the world's adult population. While it is associated with obesity and metabolic syndrome …