Function and biogenesis of lipopolysaccharides

B Bertani, N Ruiz - Ecosal plus, 2018 - Am Soc Microbiol
The cell envelope is the first line of defense between a bacterium and the world-at-large.
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …

Pushing the envelope: LPS modifications and their consequences

BW Simpson, MS Trent - Nature Reviews Microbiology, 2019 - nature.com
The defining feature of the Gram-negative cell envelope is the presence of two cellular
membranes, with the specialized glycolipid lipopolysaccharide (LPS) exclusively found on …

A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

The dual role of lipopolysaccharide as effector and target molecule

A Wiese, K Brandenburg, AJ Ulmer, U Seydel… - 1999 - degruyter.com
Lipopolysaccharides (LPS) are major integral components of the outer membrane of Gram-
negative bacteria being exclusively located in its outer leaflet facing the bacterial …

Endotoxins: lipopolysaccharides of gram-negative bacteria

X Wang, PJ Quinn - Endotoxins: structure, function and recognition, 2010 - Springer
Endotoxin refers lipopolysaccharide that constitutes the outer leaflet of the outer membrane
of most Gram-negative bacteria. Lipopolysaccharide is comprised of a hydrophilic …

Functional Analysis of the Protein Machinery Required for Transport of Lipopolysaccharide to the Outer Membrane of Escherichia coli

P Sperandeo, FK Lau, A Carpentieri… - Journal of …, 2008 - Am Soc Microbiol
Lipopolysaccharide (LPS) is an essential component of the outer membrane (OM) in most
gram-negative bacteria, and its structure and biosynthetic pathway are well known …

Regulated assembly of LPS, its structural alterations and cellular response to LPS defects

G Klein, S Raina - International journal of molecular sciences, 2019 - mdpi.com
Distinguishing feature of the outer membrane (OM) of Gram-negative bacteria is its
asymmetry due to the presence of lipopolysaccharide (LPS) in the outer leaflet of the OM …

Invited review: diversity of endotoxin and its impact on pathogenesis

MS Trent, CM Stead, AX Tran… - Journal of endotoxin …, 2006 - journals.sagepub.com
Lipopolysaccharide or LPS is localized to the outer leaflet of the outer membrane and serves
as the major surface component of the bacterial cell envelope. This remarkable glycolipid is …

[HTML][HTML] Structural and functional analyses of bacterial lipopolysaccharides

M Caroff, D Karibian, JM Cavaillon… - Microbes and …, 2002 - Elsevier
Bacterial lipopolysaccharides (LPSs) are powerful immunomodulators in infected hosts, and
may cause endotoxic shock. Most of them share a common architecture but vary …

Lipopolysaccharide: Biosynthetic pathway and structure modification

X Wang, PJ Quinn - Progress in lipid research, 2010 - Elsevier
Lipopolysaccharide that constitutes the outer leaflet of the outer membrane of most Gram-
negative bacteria is referred to as an endotoxin. It is comprised of a hydrophilic …