The practice of HDX-MS remains somewhat difficult, not only for newcomers but also for
veterans, despite its increasing popularity. While a typical HDX-MS project starts with a …

Hydrogen Deuterium Exchange (HDX) Mass Spectrometry (MS) is a sensitive analytical
technique that provides information on protein conformation and dynamics in solution. It is …

Hydrogen deuterium exchange measured by mass spectrometry (HDX-MS) is a commonly
used technique for studying the structural dynamics of proteins in solution. The first part of …

For hydrogen–deuterium exchange mass spectrometry (HDX-MS) to have an increased role
in quality control of biopharmaceuticals, H for D back-exchange occurring during protein …

Hydrogen/deuterium exchange (HDX) methods generate useful information on protein
structure and dynamics, ideally at the individual residue level. Most MS-based HDX methods …

Protein hydrogen/deuterium exchange (HDX) followed by protease digestion and mass
spectrometric (MS) analysis is accepted as a standard method for studying protein …

Hydrogen–deuterium exchange (HDX) experiments analyzed by mass spectrometry (MS)
provide information about the dynamics and the solvent accessibility of protein backbone …

The addition of mass spectrometry (MS) analysis to the hydrogen exchange (HX) proteolytic
fragmentation experiment extends powerful HX methodology to the study of large …

The data analysis practices associated with hydrogen–deuterium exchange mass
spectrometry (HX-MS) lag far behind that of most other MS-based protein analysis tools. A …

A major component of a hydrogen exchange mass spectrometry experiment is the analysis
of protein and peptide mass spectra to yield information about deuterium incorporation. The …