Time is spine: a review of translational advances in spinal cord injury: JNSPG 75th Anniversary Invited Review Article

JH Badhiwala, CS Ahuja, MG Fehlings - Journal of Neurosurgery: Spine, 2018 - thejns.org
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical,
emotional, and economic consequences for patients, families, and society at large. Timely …

A clinical practice guideline for the management of patients with acute spinal cord injury and central cord syndrome: recommendations on the timing (≤ 24 hours …

MG Fehlings, LA Tetreault, JR Wilson… - Global spine …, 2017 - journals.sagepub.com
Objective: To develop recommendations on the timing of surgical decompression in patients
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …

Optimal timing of surgical decompression for acute traumatic central cord syndrome: a systematic review of the literature

KK Anderson, L Tetreault, MF Shamji, A Singh… - …, 2015 - journals.lww.com
BACKGROUND: Traumatic central cord syndrome (TCCS) is an incomplete spinal cord
injury defined by greater weakness in upper versus lower extremities, variable sensory loss …

[HTML][HTML] Guidelines for the conduct of clinical trials in spinal cord injury: Neuroimaging biomarkers

M Seif, CAM Gandini Wheeler-Kingshott… - Spinal Cord, 2019 - nature.com
Traumatic spinal cord injury (SCI) leads to immediate neuronal and axonal damage at the
focal injury site and triggers secondary pathologic series of events resulting in sensorimotor …

Early surgery for traumatic spinal cord injury: where are we now?

JR Wilson, CD Witiw, J Badhiwala… - Global spine …, 2020 - journals.sagepub.com
Study Design: Narrative review. Objective: There is a strong biological rationale to perform
early decompression after traumatic spinal cord injury (SCI). With an enlarging clinical …

Spinal cord injury—what are the controversies?

CS Ahuja, GD Schroeder, AR Vaccaro… - Journal of orthopaedic …, 2017 - journals.lww.com
Traumatic spinal cord injuries have a tremendous impact on individuals, families, and
society as a whole. Substantial heterogeneity in the patient population, their presentation …

Timing of decompressive surgery of spinal cord after traumatic spinal cord injury: an evidence-based examination of pre-clinical and clinical studies

JC Furlan, V Noonan, DW Cadotte… - Journal of …, 2011 - liebertpub.com
While the recommendations for spine surgery in specific cases of acute traumatic spinal cord
injury (SCI) are well recognized, there is considerable uncertainty regarding the role of the …

[HTML][HTML] “Time is spine”: the importance of early intervention for traumatic spinal cord injury

CS Ahuja, JH Badhiwala, MG Fehlings - Spinal Cord, 2020 - nature.com
Traumatic spinal cord injuries (SCI) have devastating lifelong sequelae for affected
individuals, caregivers, and society. Modest improvements in sensorimotor function can …

The urgency of surgical decompression in acute central cord injuries with spondylosis and without instability

B Lenehan, CG Fisher, A Vaccaro, M Fehlings… - Spine, 2010 - journals.lww.com
Study Design. Systematic review, ambispective analysis of observational data. Objective. To
make recommendations as to whether or not urgent surgical decompression is ever …

The timing of surgical intervention in the treatment of spinal cord injury: a systematic review of recent clinical evidence

MG Fehlings, RG Perrin - Spine, 2006 - journals.lww.com
Study Design. Evidence-based literature review. Objective. To provide updated evidence-
based recommendations regarding spinal cord decompression in patients with acute spinal …