Brief report: weight gain in persons with HIV switched from efavirenz-based to integrase strand transfer inhibitor–based regimens

J Norwood, M Turner, C Bofill, P Rebeiro… - JAIDS Journal of …, 2017 - journals.lww.com
Background: With the introduction of integrase strand transfer inhibitor (INSTI)-based
antiretroviral therapy, persons living with HIV have a potent new treatment option. Recently …

No overall change in the rate of weight gain after switching to an integrase-inhibitor in virologically suppressed adults with HIV

JE Burns, OT Stirrup, D Dunn, I Runcie-Unger… - Aids, 2020 - journals.lww.com
Objective: Excessive weight gain has been reported with integrase strand transfer inhibitors
(INSTIs). We evaluated weight changes in virologically suppressed adults with HIV who …

Efavirenz pharmacogenetics and weight gain following switch to integrase inhibitor–containing regimens

MA Leonard, Z Cindi, Y Bradford… - Clinical Infectious …, 2021 - academic.oup.com
Background Unwanted weight gain affects some people living with human
immunodeficiency virus (HIV) who are prescribed integrase strand transfer inhibitors …

Weight gain and metabolic effects in persons with HIV who switch to ART regimens containing integrase inhibitors or tenofovir alafenamide

FJ Palella, Q Hou, J Li, J Mahnken… - JAIDS Journal of …, 2023 - journals.lww.com
Background: The timing and magnitude of antiretroviral therapy–associated weight change
attributions are unclear. Setting: HIV Outpatient Study participants. Methods: We analyzed …

Risk factors for weight gain following switch to integrase inhibitor–based antiretroviral therapy

JE Lake, K Wu, SH Bares, P Debroy… - Clinical Infectious …, 2020 - academic.oup.com
Background Treatment initiation with integrase strand transfer inhibitors (INSTIs) has been
associated with excess weight gain. Whether similar gains are seen after switch to INSTIs …

Weight gain among treatment‐naïve persons with HIV starting integrase inhibitors compared to non‐nucleoside reverse transcriptase inhibitors or protease inhibitors …

K Bourgi, CA Jenkins, PF Rebeiro… - Journal of the …, 2020 - Wiley Online Library
Introduction Weight gain following antiretroviral therapy (ART) initiation is common,
potentially predisposing some persons with HIV (PWH) to cardio‐metabolic disease. We …

Greater weight gain in treatment-naive persons starting dolutegravir-based antiretroviral therapy

K Bourgi, PF Rebeiro, M Turner… - Clinical Infectious …, 2020 - academic.oup.com
Background Recent studies have reported weight gain in virologically suppressed persons
living with human immunodeficiency virus (PLWH) switched from older antiretroviral therapy …

Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: a network meta-analysis

R Bai, S Lv, H Wu, L Dai - BMC infectious diseases, 2022 - Springer
Background Global antiretroviral therapy has entered a new era. Integrase strand transfer
inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) …

Relationship between weight gain and insulin resistance in people living with HIV switching to integrase strand transfer inhibitors-based regimens

J Milic, S Renzetti, D Ferrari, S Barbieri, M Menozzi… - Aids, 2022 - journals.lww.com
Objective: The primary objective was to explore weight and BMI changes in people with HIV
(PWH) undergoing integrase strand transfer inhibitors (INSTI)-based regimens (vs. non …

Weight gain associated with integrase stand transfer inhibitor use in women

AM Kerchberger, AN Sheth, CD Angert… - Clinical infectious …, 2020 - academic.oup.com
Background Integrase strand-transfer inhibitor (INSTI)-based antiretroviral therapy (ART) is
recommended for human immunodeficiency virus (HIV) management. Although studies …