[HTML][HTML] Cannabinoids and epilepsy

EC Rosenberg, RW Tsien, BJ Whalley, O Devinsky - Neurotherapeutics, 2015 - Elsevier
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

The pharmacological basis of cannabis therapy for epilepsy

DS Reddy, VM Golub - Journal of Pharmacology and Experimental …, 2016 - ASPET
Recently, cannabis has been suggested as a potential alternative therapy for refractory
epilepsy, which affects 30% of epilepsy, both adults and children, who do not respond to …

[HTML][HTML] Cannabinoids in the treatment of epilepsy: hard evidence at last?

E Perucca - Journal of epilepsy research, 2017 - ncbi.nlm.nih.gov
The interest in cannabis-based products for the treatment of refractory epilepsy has
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …

Cannabis and endocannabinoid signaling in epilepsy

I Katona - Endocannabinoids, 2015 - Springer
The antiepileptic potential of Cannabis sativa preparations has been historically recognized.
Recent changes in legal restrictions and new well-documented cases reporting remarkably …

Cannabis for pediatric epilepsy

RJ Huntsman, R Tang-Wai… - Journal of Clinical …, 2020 - journals.lww.com
Epilepsy is a chronic disease characterized by recurrent unprovoked seizures. Up to 30% of
children with epilepsy will be refractory to standard anticonvulsant therapy, and those with …

Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection

EC Rosenberg, PH Patra, BJ Whalley - Epilepsy & Behavior, 2017 - Elsevier
The isolation and identification of the discrete plant cannabinoids in marijuana revived
interest in analyzing historical therapeutic claims made for cannabis in clinical case studies …

[HTML][HTML] Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures

NA Jones, SE Glyn, S Akiyama, TDM Hill, AJ Hill… - Seizure, 2012 - Elsevier
Cannabis sativa has been associated with contradictory effects upon seizure states despite
its medicinal use by numerous people with epilepsy. We have recently shown that the …

Cannabis for the treatment of epilepsy: an update

TE Gaston, JP Szaflarski - Current neurology and neuroscience reports, 2018 - Springer
Abstract Purpose of Review For millennia, there has been interest in the use of cannabis for
the treatment of epilepsy. However, it is only recently that appropriately powered controlled …

The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights

W Lazarini-Lopes, RA Do Val-da Silva… - Neuroscience & …, 2020 - Elsevier
Epilepsy is a neurological disorder characterized by the presence of seizures and
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …

Cannabidiol therapy for refractory epilepsy and seizure disorders

V Golub, DS Reddy - Cannabinoids and neuropsychiatric disorders, 2021 - Springer
Cannabis-derived cannabinoids have neuroactive properties. Recently, there has been
emerging interest in the use of cannabidiol (CBD)-enriched products for treatment of drug …