[HTML][HTML] High-dose nebulized colistin methanesulfonate and the role in hospital-acquired pneumonia caused by Gram-negative bacteria with difficult-to-treat …

I Karaiskos, A Gkoufa, E Polyzou, G Schinas… - Microorganisms, 2023 - mdpi.com
Hospital-acquired pneumonia, including ventilator-associated pneumonia (VAP) due to
difficult-to-treat-resistant (DTR) Gram-negative bacteria, contributes significantly to morbidity …

[HTML][HTML] Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: a prospective study

A Michalopoulos, D Fotakis, S Virtzili, C Vletsas… - Respiratory …, 2008 - Elsevier
BACKGROUND: Ventilator-associated pneumonia (VAP) remains the leading cause of
death in patients with intensive care unit (ICU) acquired infections associated with an …

Colistin for the treatment of ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: a systematic review and meta-analysis

WJ Gu, F Wang, L Tang, J Bakker, JC Liu - International journal of …, 2014 - Elsevier
Ventilator-associated pneumonia (VAP) caused by multidrug-resistant (MDR) Gram-
negative bacteria (GNB) has emerged as an important and intractable clinical problem. This …

[HTML][HTML] Can nebulised colistin therapy improve outcomes in critically ill children with multi-drug resistant gram-negative bacterial pneumonia?

F Aygun, FD Aygun, F Varol, C Durak, H Cokugraş… - Antibiotics, 2019 - mdpi.com
In the past decade, multidrug-resistant (MDR) gram-negative bacteria have become a major
problem, especially for patients in intensive care units. Recently, colistin became the last …

[HTML][HTML] Efficacy and safety of adjunctive nebulized colistin sulfate for multidrug-resistant Gram-negative bacteria pneumonia: a retrospective comparative cohort study

XL Bao, T Tao, N Tang, YZ Wang… - Annals of Palliative …, 2022 - apm.amegroups.org
Background: The incidence of multidrug-resistant Gram-negative bacteria (MDR-GNB)
pneumonia has increased in the last decade. If antibiotics are given only through …

[HTML][HTML] Adjunctive aerosolized colistin for multi-drug resistant gram-negative pneumonia in the critically ill: a retrospective study

NM Doshi, CH Cook, KL Mount, SP Stawicki… - BMC …, 2013 - Springer
Background The incidence of multi-drug resistant (MDR) gram-negative (GN) organisms
including Pseudomonas and Acinetobacter spp has increased in the last decade, prompting …

[HTML][HTML] Efficacy of adjunctive nebulized colistin in critically ill patients with nosocomial carbapenem-resistant Gram-negative bacterial pneumonia: a multi-centre …

JY Feng, CK Peng, CC Sheu, YC Lin, MC Chan… - Clinical Microbiology …, 2021 - Elsevier
Objectives To investigate the association between adjunctive nebulized colistin and
treatment outcomes in critically ill patients with nosocomial carbapenem-resistant Gram …

Inhalation with intravenous loading dose of colistin in critically ill patients with pneumonia caused by carbapenem-resistant gram-negative bacteria

J Choe, YM Sohn, SH Jeong, HJ Park… - Therapeutic …, 2019 - journals.sagepub.com
Background: Despite the increasing use of colistin in clinical practice, the optimal dosing,
and administration route have not been established. This study aimed to evaluate the …

[HTML][HTML] Nebulized colistin as the adjunctive treatment for ventilator-associated pneumonia: A systematic review and meta-analysis

X Zhang, X Cui, M Jiang, S Huang, M Yang - Journal of critical care, 2023 - Elsevier
Purpose Nebulized colistin (NC) is a potential therapy for ventilator-associated pneumonia
(VAP); however, the clinical efficacy and safety of NC remain unclear. This study …

[HTML][HTML] Pharmacokinetic characteristics of nebulized colistimethate sodium using two different types of nebulizers in critically ill patients with ventilator-associated …

A Kyriakoudi, K Pontikis, G Valsami, S Avgeropoulou… - Antibiotics, 2022 - mdpi.com
Background: Rising antimicrobial resistance has led to a revived interest in inhaled colistin
treatment in the critically ill patient with ventilator-associated respiratory infection (VARI) …