High N6‐methyladenosine‐activated TCEAL8 mRNA is a novel pancreatic cancer marker

T Hara, S Meng, H Sato, S Tatekawa, K Sasaki… - Cancer …, 2024 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) is an RNA modification involved in RNA processing
and widely found in transcripts. In cancer cells, m6A is upregulated, contributing to their …

The emerging Role of RNA N6-methyladenosine modification in pancreatic cancer

X Hu, X Lei, J Guo, W Fu, W Sun, Q Lu, W Su… - Frontiers in …, 2022 - frontiersin.org
Pancreatic cancer (PC) is one of the most common malignant cancers, ranking the seventh
highest causes of cancer-related deaths globally. Recently, RNA N6-methyladenosine …

[HTML][HTML] N6-methyladenosine (m6A) in pancreatic cancer: Regulatory mechanisms and future direction

J Li, F Wang, Y Liu, H Wang, B Ni - International Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract N 6-methyladenosine (m 6 A), the most abundant RNA modification in eukaryotes,
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …

Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing

Z Zhang, Q Wang, M Zhang, W Zhang, L Zhao… - Epigenetics, 2021 - Taylor & Francis
Accumulating evidence has demonstrated that N6-methyladenosine (m6A) plays important
roles in various cancers, making it essential to profile m6A modifications at a transcriptome …

Comprehensive analysis of the transcriptome-wide m6A methylome in lung adenocarcinoma by MeRIP sequencing

W Mao, Q Yu, K Wang, Q Ma, Y Zheng, G Zhang… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant internal modification on eukaryotic
mRNAs. There is increasing evidence that m6A plays a key role in tumor progression, so it is …

Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers

D Ramasamy, M Thippannah, HRP Maharajan… - Molecular Biology …, 2024 - Springer
Abstract Background N6-methyladenosine (m6A) is a prevalent and crucial RNA methylation
modification that plays a significant role in various biological and pathological processes …

Comprehensive analysis of differentially expressed profiles of mRNA N6-methyladenosine in colorectal cancer

N Li, Q Guo, Q Zhang, BJ Chen, XA Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Aim: To comprehensively profile the landscape of the mRNA N6-methyladenosine (m6A)
modification in human colorectal cancer (CRC). Methods: Methylated RNA …

Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer

M Wang, J Liu, Y Zhao, R He, X Xu, X Guo, X Li, S Xu… - Molecular cancer, 2020 - Springer
Background Pancreatic cancer is one of the most lethal human cancers. N 6-
methyladenosine (m 6 A), a common eukaryotic mRNA modification, plays critical roles in …

The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells

K Taketo, M Konno, A Asai… - International …, 2017 - spandidos-publications.com
N 6-methyladenosine (m6A) is the most abundant epitranscriptome modification in
mammalian mRNA. Recent years have seen substantial progress in m6A epitranscriptomics …

Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent …

Y Zhou, Z Yin, B Hou, M Yu, R Chen… - Cancer management …, 2019 - Taylor & Francis
Background: N6-methyladenosine (m6A) is the most prevalent modification of mammalian
RNA. Emerging evidence suggest that m6A has critical roles in multiple biological activities …