Impact of soy isoflavones on the epigenome in cancer prevention

M Pudenz, K Roth, C Gerhauser - Nutrients, 2014 - mdpi.com
Isoflavones (IF) such as genistein are cancer preventive phytochemicals found in soy and
other legumes. Epidemiological studies point to a reduced risk for hormone‑dependent …

Genistein, an epigenome modifier during cancer prevention

Y Zhang, H Chen - Epigenetics, 2011 - Taylor & Francis
Dietary compounds have been observed to have a great potential to regulate the
epigenome, which is disrupted and reprogrammed during carcinogenesis. Because of their …

Soy isoflavones and cancer prevention: clinical science review

FH Sarkar, Y Li - Cancer investigation, 2003 - Taylor & Francis
Epidemiological studies have shown a significant difference in cancer incidence among
different ethnic groups, which is believed to be partly attributed to dietary habits. The …

Mechanisms of cancer chemoprevention by soy isoflavone genistein

FH Sarkar, Y Li - Cancer and Metastasis Reviews, 2002 - Springer
Diet has been implicated to play an important role in cancers. Epidemiological studies have
revealed that Asians, who consume a traditional diet high in soy products, have relatively …

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

IMCM Rietjens, AM Sotoca, J Vervoort… - Molecular nutrition & …, 2013 - Wiley Online Library
Isoflavones are phytoestrogens that have been linked to both beneficial as well as adverse
effects in relation to cell proliferation and cancer risks. The present article presents an …

Effect of dietary genistein on Phase II and antioxidant enzymes in rat liver

H Wiegand, AE Wagner… - Cancer genomics & …, 2009 - cgp.iiarjournals.org
Isoflavones are thought to be biologically active components in soy that play a role in the
prevention of chronic diseases including cancer. How isoflavones may mediate their …

[HTML][HTML] Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in androgen-independent PC-3 human prostate cancer …

R Handayani, L Rice, Y Cui, TA Medrano… - The Journal of …, 2006 - Elsevier
High consumption of soy isoflavones in Asian diets has been correlated with a lower
incidence of clinically important cases of prostate cancer. The chemopreventive properties of …

Multi-targeted therapy of cancer by genistein

S Banerjee, Y Li, Z Wang, FH Sarkar - Cancer letters, 2008 - Elsevier
Soy isoflavones have been identified as dietary components having an important role in
reducing the incidence of breast and prostate cancers in Asian countries. Genistein, the …

[HTML][HTML] Current perspectives on the beneficial effects of soybean isoflavones and their metabolites for humans

IS Kim - Antioxidants, 2021 - mdpi.com
Soybeans are rich in proteins and lipids and have become a staple part of the human diet.
Besides their nutritional excellence, they have also been shown to contain various functional …

[HTML][HTML] Genistein and cancer: current status, challenges, and future directions

C Spagnuolo, GL Russo, IE Orhan, S Habtemariam… - Advances in …, 2015 - Elsevier
Primary prevention through lifestyle interventions is a cost-effective alternative for preventing
a large burden of chronic and degenerative diseases, including cancer, which is one of the …