[PDF][PDF] Pyrazolopyrimidines: Synthesis, Chemical Reactions and Biological Activity

SA Ahmed, HS Elgendy, WO Younis - International Journal, 2014 - researchgate.net
Chemistry associated with genes has attracted a great public interest during the last two
decades. Nucleotides are the backbone of the nucleic acid molecule. The common …

A REVIEW: PYRAZOLOPYRIMIDINE MOIETY.

S Singh, PK Sharma, R Dudhe… - Pharma Science …, 2011 - search.ebscohost.com
Pyrazole and pyrimidine derivatives attracted organic chemists due to their various
biological and chemotherapeutic significance. Pyrazolopyrimidines and related fused …

[PDF][PDF] Synthesis of some pyrazolopyrimidines as purine analogues

SA Ahmed, AM Hussein, WGM Hozayen… - Journal of heterocyclic …, 2007 - academia.edu
Purine analogues are well known for their importance in biological applications as
antimetabolites [1], especially in the treatment of cancer and viral diseases. Also, purines are …

An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity

RN Rao, K Chanda - Bioorganic Chemistry, 2020 - Elsevier
Heterocyclic compounds with nitrogen atom play a key role in the normal life cycle of a cell.
Pyrazolopyrimidine is a privileged class of nitrogen containing fused heterocyclic compound …

Synthesis of novel pyrazolopyridine and pyridopyrimidine derivatives.

AM Soliman - Journal of Heterocyclic Chemistry, 2011 - search.ebscohost.com
Pyridine, pyrazole, and pyrimidine derivatives attracted organic chemists very much due to
their biological and chemotherapeutic importance. Pyridobenzodiazepine derivatives [1–3] …

Pyrazolopyrimidine nucleosides. 12. Synthesis and biological activity of certain pyrazolo [3, 4-d] pyrimidine nucleosides related to adenosine

GA Bhat, JLG Montero, RP Panzica… - Journal of Medicinal …, 1981 - ACS Publications
The chemical synthesis of certain 4-substituted pyrazolo [3, 4-d] pyrimidine nucleosides is
described. Using 1-(2, 3, 5-tri-0-acetyl-/3-i> ribofuranosyl) pyrazolo [3, 4-d] pyrimidin-4-one …

[PDF][PDF] Synthesis, Characterization and Biological evaluation of some Novel Pyrazolo [3, 4-b] pyridin-3-amine derivatives.

A Bhatt, RK Singh, R Kant… - Chemistry & Biology …, 2016 - cbijournal.com
A large number of heterocyclic compounds containing pyridine rings are associated with
diverse pharmacological properties such as antimicrobial [1, 2], anticancer [3] anticonvulsant …

Recent progress in the synthesis of pyrazolopyridines and their derivatives

SV Kumar, S Muthusubramanian… - Organic Preparations and …, 2019 - Taylor & Francis
Pyrazole and pyridine are important heterocycles whose skeletons are incorporated into
many biologically active natural products and synthetic analogues with interesting …

[引用][C] Synthesis and cytotoxic activity of 4, 6-diaminopyrazolo [3, 4-d] pyrimidine riboside and its 3-carbamoyl derivative

LD Garaeva, IA Korbukh, YV Dobrynin… - Pharmaceutical …, 1988 - Springer
A number of compounds with valuable biological properties have been found among the
pyrazolo [3, 4-d] pyrimidines and their nucleosides. Thus, experimental antitumor activity …

Design, synthesis, and characterization of novel pyrazolopyridine and pyridopyrazolopyrimidine derivatives

RM Keshk - Journal of heterocyclic Chemistry, 2022 - Wiley Online Library
Novel derivatives of pyrazolopyridine and pyridopyrazolopyrimidine were synthesized as
these nitrogen heterocyclic compounds have biological and pharmaceutical application …