Cross-kingdom cell-to-cell interactions in cariogenic biofilm initiation

SX Wan, J Tian, Y Liu, A Dhall, H Koo… - Journal of dental …, 2021 - journals.sagepub.com
Candida albicans is known to form polymicrobial biofilms with various Streptococcus spp.,
including mitis and mutans group streptococci. Streptococcus gordonii (mitis group) has …

Candida albicans Adhesins Als1 and Hwp1 Modulate Interactions with Streptococcus mutans

L Martorano-Fernandes, JS Goodwine… - Microorganisms, 2023 - mdpi.com
Candida albicans and Streptococcus mutans are known to synergistically interact with each
other in the oral cavity. For example, glucosyltransferase B (GtfB), secreted by S. mutans …

Contributions of Candida albicans dimorphism, adhesive interactions, and extracellular matrix to the formation of dual-species biofilms with Streptococcus gordonii

D Montelongo-Jauregui, SP Saville, JL Lopez-Ribot - Mbio, 2019 - Am Soc Microbiol
Fungal and bacterial populations coexist in the oral cavity, frequently forming mixed-species
biofilms that complicate treatment against polymicrobial infections. However, despite …

The Role of Candida albicans Secreted Polysaccharides in Augmenting Streptococcus mutans Adherence and Mixed Biofilm Formation: In vitro and in vivo Studies

ZH Khoury, T Vila, TR Puthran, AS Sultan… - Frontiers in …, 2020 - frontiersin.org
The oral cavity is a complex environment harboring diverse microbial species that often co-
exist within biofilms formed on oral surfaces. Within a biofilm, inter-species interactions can …

Biofilm ecology associated with dental caries: understanding of microbial interactions in oral communities leads to development of therapeutic strategies targeting …

JN Cai, D Kim - Advances in Applied Microbiology, 2023 - Elsevier
A biofilm is a sessile community characterized by cells attached to the surface and
organized into a complex structural arrangement. Dental caries is a biofilm-dependent oral …

Interkingdom cooperation between Candida albicans, Streptococcus oralis and Actinomyces oris modulates early biofilm development on denture material

IMG Cavalcanti, AH Nobbs… - FEMS Pathogens …, 2016 - academic.oup.com
Candida-associated stomatitis affects up to 60% of denture wearers, and Candida albicans
remains the most commonly isolated fungal species. The oral bacteria Actinomyces oris and …

Spatial distribution and chemical tolerance of Streptococcus mutans within dual-species cariogenic biofilms

Y Nakanishi, T Yamamoto, N Obana… - Microbes and …, 2018 - jstage.jst.go.jp
Bacterial interspecies interactions in the oral cavity influence the structural development of
cariogenic biofilms and dental caries. Visualization of the biofilm architecture and bacterial …

Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms

Y Zeng, E Rustchenko, X Huang, TT Wu… - Journal of Oral …, 2023 - Taylor & Francis
Objective To assess the interactions between Streptococcus mutans and Candida albicans
during cariogenic biofilm formation. Methods The S. mutans and C. albicans duo-species …

Synergism of Streptococcus mutans and Candida albicans Reinforces Biofilm Maturation and Acidogenicity in Saliva: An In Vitro Study

HE Kim, Y Liu, A Dhall, M Bawazir, H Koo… - Frontiers in cellular and …, 2021 - frontiersin.org
Early childhood caries, a virulent-form of dental caries, is painful, difficult, and costly to treat
that has been associated with high levels of Streptococcus mutans (Sm) and Candida …

Candida albicans in oral biofilms could prevent caries

HM Willems, K Kos, MA Jabra-Rizk… - FEMS Pathogens and …, 2016 - academic.oup.com
Streptococcus mutans is a Gram-positive bacterium involved in development to caries, the
most common infectious disease of our time. Streptococcus mutans interacts with other …