[HTML][HTML] Neuroinflammation of microglia polarization in intracerebral hemorrhage and its potential targets for intervention

G Yang, X Fan, M Mazhar, W Guo, Y Zou… - Frontiers in Molecular …, 2022 - frontiersin.org
Microglia are the resident immune cells of the central nervous system (CNS) and play a key
role in neurological diseases, including intracerebral hemorrhage (ICH). Microglia are …

[HTML][HTML] Microglia: a double-edged sword in intracerebral hemorrhage from basic mechanisms to clinical research

J Liu, L Liu, X Wang, R Jiang, Q Bai… - Frontiers in …, 2021 - frontiersin.org
Microglia are the resident immune cells of the central nervous system (CNS). It is well
established that microglia are activated and polarized to acquire different inflammatory …

[HTML][HTML] Microglia phenotype and intracerebral hemorrhage: A Balance of Yin and Yang

R Bi, Z Fang, M You, Q He, B Hu - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) features extremely high rates of morbidity and mortality, with
no specific and effective therapy. And local inflammation caused by the over-activated …

[HTML][HTML] Mechanism and regulation of microglia polarization in intracerebral hemorrhage

Y Guo, W Dai, Y Zheng, W Qiao, W Chen, L Peng… - Molecules, 2022 - mdpi.com
Intracerebral hemorrhage (ICH) is the most lethal subtype of stroke, but effective treatments
are lacking, and neuroinflammation plays a key role in the pathogenesis. In the innate …

Modulators of microglial activation and polarization after intracerebral haemorrhage

X Lan, X Han, Q Li, QW Yang, J Wang - Nature Reviews Neurology, 2017 - nature.com
Intracerebral haemorrhage (ICH) is the most lethal subtype of stroke but currently lacks
effective treatment. Microglia are among the first non-neuronal cells on the scene during the …

Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage

CF Chang, J Wan, Q Li, SC Renfroe, NM Heller… - Neurobiology of …, 2017 - Elsevier
Microglia/macrophages (MMΦ) are highly plastic phagocytes that can promote both injury
and repair in diseased brain through the distinct function of classically activated and …

[HTML][HTML] Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarachnoid hemorrhage

J Chen, ZV Zheng, G Lu, WY Chan… - Neural regeneration …, 2022 - journals.lww.com
Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity,
despite advances in treating cerebral aneurysms. There has been recent progress in the …

[HTML][HTML] Neuroinflammation after intracerebral hemorrhage

E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities

Q Bai, M Xue, VW Yong - Brain, 2020 - academic.oup.com
The prognosis of intracerebral haemorrhage continues to be devastating despite much
research into this condition. A prominent feature of intracerebral haemorrhage is …

Microglia/macrophage polarization after experimental intracerebral hemorrhage

H Zhao, T Garton, RF Keep, Y Hua, G Xi - Translational stroke research, 2015 - Springer
Microglia are the resident macrophages of the brain and are the first responders to immune
system activation in that tissue. Under resting conditions, microglia are ramified and monitor …