Diabetic nephropathy alters the distribution of circulating angiogenic microRNAs among extracellular vesicles, HDL, and Ago-2
BW Florijn, JMGJ Duijs, JH Levels… - Diabetes, 2019 - Am Diabetes Assoc
Previously, we identified plasma microRNA (miR) profiles that associate with markers of
microvascular injury in patients with diabetic nephropathy (DN). However, miRs circulate in …
microvascular injury in patients with diabetic nephropathy (DN). However, miRs circulate in …
Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
Rationale: MicroRNAs (miRNAs) have been implicated in the epigenetic regulation of key
metabolic, inflammatory, and antiangiogenic pathways in type 2 diabetes (DM) and may …
metabolic, inflammatory, and antiangiogenic pathways in type 2 diabetes (DM) and may …
MicroRNA-mediated vascular intercellular communication is altered in chronic kidney disease
A Zietzer, E Steffen, S Niepmann… - Cardiovascular …, 2022 - academic.oup.com
Aims Chronic kidney disease (CKD) is an independent risk factor for the development of
coronary artery disease (CAD). For both, CKD and CAD, the intercellular transfer of …
coronary artery disease (CAD). For both, CKD and CAD, the intercellular transfer of …
Hyperglycemia inhibition of endothelial miR-140-3p mediates angiogenic dysfunction in diabetes mellitus
D Wang, H Wang, C Liu, X Mu, S Cheng - Journal of Diabetes and its …, 2019 - Elsevier
Objective MicroRNAs (miRNAs) have emerged as promising regulators of diabetes mellitus
(DM)-induced angiogenic dysfunction in endothelial cells (ECs), but information vis-à-vis the …
(DM)-induced angiogenic dysfunction in endothelial cells (ECs), but information vis-à-vis the …
Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy
S Rawal, PE Munasinghe, A Shindikar… - Cardiovascular …, 2017 - academic.oup.com
Aim Microangiopathy due to endothelial dysfunction is a major contributing factor to the
development of diabetes-induced cardiovascular disease (CVD). Dysregulation of …
development of diabetes-induced cardiovascular disease (CVD). Dysregulation of …
[HTML][HTML] Circulating microRNAs associate with diabetic nephropathy and systemic microvascular damage and normalize after simultaneous pancreas–kidney …
R Bijkerk, J Duijs, M Khairoun, CJH Ter Horst… - American Journal of …, 2015 - Elsevier
Because microvascular disease is one of the most important drivers of diabetic
complications, early monitoring of microvascular integrity may be of clinical value. By …
complications, early monitoring of microvascular integrity may be of clinical value. By …
Angiogenic microRNAs linked to incidence and progression of diabetic retinopathy in type 1 diabetes
Circulating microRNAs (miRNAs) have emerged as novel biomarkers of diabetes. The
current study focuses on the role of circulating miRNAs in patients with type 1 diabetes and …
current study focuses on the role of circulating miRNAs in patients with type 1 diabetes and …
[HTML][HTML] Vascular endothelial microparticles-incorporated microRNAs are altered in patients with diabetes mellitus
F Jansen, H Wang, D Przybilla, BS Franklin… - Cardiovascular …, 2016 - Springer
Abstract Background Circulating microRNAs (miRs) are differentially regulated and
selectively packaged into microparticles (MPs). We evaluated whether diabetes mellitus …
selectively packaged into microparticles (MPs). We evaluated whether diabetes mellitus …
Deregulation of microRNA-503 contributes to diabetes mellitus–induced impairment of endothelial function and reparative angiogenesis after limb ischemia
A Caporali, M Meloni, C Völlenkle, D Bonci… - Circulation, 2011 - Am Heart Assoc
Background—Diabetes mellitus impairs endothelial cell (EC) function and postischemic
reparative neovascularization by molecular mechanisms that are not fully understood …
reparative neovascularization by molecular mechanisms that are not fully understood …
[HTML][HTML] Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury
Y Huang, Y Liu, L Li, B Su, L Yang, W Fan, Q Yin… - BMC nephrology, 2014 - Springer
Background MicroRNAs have been demonstrated to play an important role in the
pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire …
pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire …
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