It has been increasingly recognized that tumor microenvironment plays an important role in
carcinogenesis. Inflammatory component is present and contributes to tumor proliferation …

Metastatic disease is the major challenge of cancer that accounts for over 90% of total
cancer lethality. Mounting clinical and preclinical data now indicate that inflammation, a …

[Frontiers in Bioscience S2, 176-183, January 1, 2010] 176 Roles of inflammation in cancer
initiation, progression, and metastas Page 1 [Frontiers in Bioscience S2, 176-183, January 1 …

Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

Inflammation has long been thought to contribute to the development of cancer; however
there is also clear evidence that the immune system can recognize and eliminate cancer …

Abstract Treatment of cancer metastasis has been largely ineffective. It is paramount to
understand the mechanisms underlying the metastatic process, of which the tumor …

Purpose Cancer cells, despite stemming from the own cells of their host, usually elicit an
immune response. This response usually enables elimination of cancer at its earliest stages …

Inflammation has been suggested to represent the seventh hallmark of cancer.
Myelomonocytic cells are a key component of cancer-related inflammation. Tumor …

Inflammatory mediators in tumor microenvironment influence cancer occurrence, growth and
metastasis through complex signaling networks. Excessive inflammation is closely …

Historically, the link between chronic inflammation and cancer has long been speculated.
Only more recently, pre-clinical and epidemiologic data as well as clinical evidence all point …