Obesity and cancer: mechanistic insights from transdisciplinary studies
EH Allott, SD Hursting - Endocrine-related cancer, 2015 - erc.bioscientifica.com
Obesity is associated with a range of health outcomes that are of clinical and public health
significance, including cancer. Herein, we summarize epidemiologic and preclinical …
significance, including cancer. Herein, we summarize epidemiologic and preclinical …
Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue
SD Hursting, SM Dunlap - Annals of the New York Academy of …, 2012 - Wiley Online Library
Obesity is an established risk and progression factor for many cancers. In the United States
more than one‐third of adults, and nearly one in five children, are currently obese. Thus, a …
more than one‐third of adults, and nearly one in five children, are currently obese. Thus, a …
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
EE Calle, R Kaaks - Nature Reviews Cancer, 2004 - nature.com
The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …
associated obesity with a range of cancer types, although the mechanisms by which obesity …
Obesity and cancer—mechanisms underlying tumour progression and recurrence
Over the past several years, the field of cancer research has directed increased interest
towards subsets of obesity-associated tumours, which include mammary, renal …
towards subsets of obesity-associated tumours, which include mammary, renal …
A weighty problem: metabolic perturbations and the obesity-cancer link
CH O'Flanagan, LW Bowers… - … molecular biology and …, 2015 - degruyter.com
Obesity is an established risk factor for several cancers, including breast, colon, endometrial,
ovarian, gastric, pancreatic and liver, and is increasingly a public health concern. Obese …
ovarian, gastric, pancreatic and liver, and is increasingly a public health concern. Obese …
Reducing the weight of cancer: mechanistic targets for breaking the obesity–carcinogenesis link
SD Hursting, LM Lashinger, KW Wheatley… - Best practice & research …, 2008 - Elsevier
The prevalence of obesity, an established epidemiologic risk factor for many cancers, has
risen steadily for the past several decades in the US. The increasing rates of obesity among …
risen steadily for the past several decades in the US. The increasing rates of obesity among …
Association of obesity-related metabolic disruptions with cancer risk and outcome
AE Lohmann, PJ Goodwin, RT Chlebowski… - Journal of Clinical …, 2016 - ascopubs.org
Over the past 40 years, the prevalence of obesity has increased epidemically worldwide,
which raises significant concerns regarding public health and the associated economic …
which raises significant concerns regarding public health and the associated economic …
Obesity and cancer: local and systemic mechanisms
NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …
Physiological and environmental factors affecting cancer risk and prognosis in obesity
PFS Etet, L Vecchio, AHN Kamdje, PN Mimche… - Seminars in Cancer …, 2023 - Elsevier
Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …
imbalance between energy intake and expenditure. Available epidemiological and clinical …
[HTML][HTML] Obesity, metabolism and the microenvironment: Links to cancer
S Sundaram, AR Johnson, L Makowski - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …
within the tumor, which informed the development of targeted therapies against affected …