Transcriptomics reveals amygdala neuron regulation by fasting and ghrelin thereby promoting feeding

C Peters, S He, F Fermani, H Lim, W Ding, C Mayer… - Science …, 2023 - science.org
The central amygdala (CeA) consists of numerous genetically defined inhibitory neurons
that control defensive and appetitive behaviors including feeding. Transcriptomic signatures …

Central amygdala circuits modulate food consumption through a positive-valence mechanism

AM Douglass, H Kucukdereli, M Ponserre… - Nature …, 2017 - nature.com
The complex behaviors underlying reward seeking and consumption are integral to
organism survival. The hypothalamus and mesolimbic dopamine system are key mediators …

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

FE Henry, K Sugino, A Tozer, T Branco, SM Sternson - Elife, 2015 - elifesciences.org
Molecular and cellular processes in neurons are critical for sensing and responding to
energy deficit states, such as during weight-loss. Agouti related protein (AGRP)-expressing …

Food cues and ghrelin recruit the same neuronal circuitry

G Van der Plasse, M Merkestein… - International journal of …, 2013 - nature.com
Background: Cues that are associated with the availability of food are known to trigger food
anticipatory activity (FAA). This activity is expressed as increased locomotor activity and …

Neural circuit mechanism underlying the feeding controlled by insula-central amygdala pathway

C Zhang-Molina, MB Schmit, H Cai - IScience, 2020 - cell.com
The Central nucleus of amygdala (CeA) contains distinct populations of neurons that play
opposing roles in feeding. The circuit mechanism of how CeA neurons process information …

Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression

CA Schiltz, QZ Bremer, CF Landry, AE Kelley - BMC biology, 2007 - Springer
Background Cues predictive of food availability are powerful modulators of appetite as well
as food-seeking and ingestive behaviors. The neurobiological underpinnings of these …

Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner

LM Lutomska, V Miok, N Krahmer, I González García… - Glia, 2022 - Wiley Online Library
Hypothalamic astrocytes are particularly affected by energy‐dense food consumption. How
the anatomical location of these glial cells and their spatial molecular distribution in the …

Neural circuit mechanisms underlying emotional regulation of homeostatic feeding

P Sweeney, Y Yang - Trends in Endocrinology & Metabolism, 2017 - cell.com
The neural circuits controlling feeding and emotional behaviors are intricately and
reciprocally connected. Recent technological developments, including cell type-specific …

New insight into GABAergic neurons in the hypothalamic feeding regulation

S Suyama, T Yada - The journal of physiological sciences, 2018 - Springer
Several lines of study have suggested that GABA in the hypothalamic feeding center plays a
role in promoting food intake. Recent studies revealed that not only NPY/AgRP neurons in …

CRH neurons in the lateral hypothalamic area regulate feeding behavior of mice

SY Li, JJ Cao, K Tan, L Fan, YQ Wang, ZX Shen, SS Li… - Current Biology, 2023 - cell.com
Food cues serve as pivotal triggers for eliciting physiological responses that subsequently
influence food consumption. The magnitude of response induced by these cues stands as a …