Introduction The prevalence of carotid artery stenosis in the general population is
approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins …

International guidelines strongly recommend statins alone or in combination with other lipid-
lowering agents to lower low-density lipoprotein cholesterol (LDL-C) levels for patients with …

OBJECTIVE: We aimed to define the role of treatment using statins (3-hydroxy-3-
methylglutaryl coenzyme A reductase inhibitors) in the management of patients with carotid …

Background and Purpose—Previously published meta-analyses exploring the effect of
statins on stroke incidence included 20 000 patients and found a 2% to 30% risk reduction. It …

Hypercholesterolemia is a risk factor for carotid artery stenosis and stroke. Statins are the
main drugs for the management of hypercholesterolemia and they are strongly …

Cerebrovascular disease is the leading cause of disability in Western societies. In the United
States, it has been estimated that a stroke occurs every 53 seconds. Consequently, the …

Observational studies suggested that the progression of carotid atherosclerosis and plaques
might be an independent risk factor for coronary artery disease (CAD) and stroke, prior …

Carotid disease may be evaluated by surrogate outcomes, such as intima-media thickness
and carotid plaque features, and by clinical end points. Statins stop progression or may …

Liu et al. reported that a 24-week treatment with rosuvastatin 10 mg/day reduced carotid
intima-media thickness (cIMT) in patients with hyperlipidemia (from 1.49±0.56 to 1.17±0.38 …

Background Statins are commonly used for the prevention of cardiovascular events;
however, statins are underutilized in patients with noncoronary atherosclerosis. We sought …