Tanshinone IIa alleviates LPS-induced oxidative stress in dairy cow mammary epithelial cells by activating the Nrf2 signalling pathway

K Fu, Y Sun, J Wang, R Cao - Research in Veterinary Science, 2022 - Elsevier
Objective Mastitis is the most prevalent disease in dairy cows worldwide. Evidence has
emerged that oxidative stress plays a crucial role in the development of mastitis. This study …

Tanshinone IIA exhibits anti-inflammatory and antioxidative effects in LPS-stimulated bovine endometrial epithelial cells by activating the Nrf2 signaling pathway

K Fu, C Feng, L Shao, L Mei, R Cao - Research in Veterinary Science, 2021 - Elsevier
Endometritis is a major disease in productive bovines, and is also caused by conditional
pathogens after delivery. The integrity and activity of bovine endometrial epithelial cells …

[HTML][HTML] Dandelion extract alleviated lipopolysaccharide-induced oxidative stress through the Nrf2 pathway in bovine mammary epithelial cells

Y Sun, Y Wu, Z Wang, J Chen, Y Yang, G Dong - Toxins, 2020 - mdpi.com
In practical dairy production, cows are frequently subjected to inflammatory diseases, such
as high-grain diet-induced subacute ruminal acidosis (SARA) as well as mastitis and …

Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells

I Ali, C Li, M Kuang, AU Shah, M Shafiq, MA Ahmad… - Molecular …, 2022 - Elsevier
Mastitis, an inflammation of the mammary gland, is a complex disease that affects the health
of dairy cows worldwide. Sodium butyrate (SB) is a short-chain fatty acid that has recently …

Oxidative stress-induced inflammatory responses and effects of N-acetylcysteine in bovine mammary alveolar cells

H Bae, CH Jeong, WN Cheng, K Hong… - Journal of Dairy …, 2017 - cambridge.org
Bovine mastitis, an inflammation of the udder, results in reduced milk production and poor
milk quality. Mastitis is usually, but not always, a response to pathogen infection. High milk …

[HTML][HTML] 2-Methyl Nonyl Ketone From Houttuynia Cordata Thunb Alleviates LPS-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial …

N Wang, Y Zhu, D Li, W Basang, Y Huang, K Liu… - Frontiers in …, 2022 - frontiersin.org
Mastitis is one of the most common diseases in dairy cows, causing huge economic losses
to the dairy industry every year. Houttuynia Cordata Thunb (H. cordata) is a traditional …

Butyrate alleviates oxidative stress by regulating NRF2 nuclear accumulation and H3K9/14 acetylation via GPR109A in bovine mammary epithelial cells and …

W Guo, J Liu, J Sun, Q Gong, H Ma, X Kan… - Free Radical Biology …, 2020 - Elsevier
Oxidative stress consistently affects lactation length and quality in dairy cows. Oxidative
stress in the mammary gland of high-yielding dairy cows is a serious problem. Therefore, we …

[HTML][HTML] Anti-inflammation of isoliquiritigenin via the inhibition of NF-κB and MAPK in LPS-stimulated MAC-T cells

M Li, G Lu, X Ma, R Wang, X Chen, Y Yu… - BMC Veterinary …, 2022 - Springer
Background The application of plant extracts has received great interest for the treatment of
bovine mastitis. Isoliquiritigenin (ISL) is a rich dietary flavonoid that has significant …

[HTML][HTML] Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model …

D Shao, W Shen, Y Miao, Z Gao, M Pan, Q Wei… - Journal of Animal …, 2023 - Springer
Background Mastitis not only deteriorates the composition or quality of milk, but also
damages the health and productivity of dairy goats. Sulforaphane (SFN) is a phytochemical …

[HTML][HTML] Green tea polyphenols alleviate hydrogen peroxide-induced oxidative stress, inflammation, and apoptosis in bovine mammary epithelial cells by activating …

Y Ma, X Ma, Y An, Y Sun, W Dou, M Li… - Frontiers in Veterinary …, 2022 - frontiersin.org
Oxidative stress (OS) is one of the main limiting factors affecting the length of lactation and
milk quality in dairy cows. For high-producing dairy cows, the OS of mammary glands is a …