Bufadienolides and their antitumor activity

H Gao, R Popescu, B Kopp, Z Wang - Natural product reports, 2011 - pubs.rsc.org
Covering: 1998 to July 2010 Since 1998, a great number of bufadienolides have been
reported from plants, animals and plant cell suspensions, as well as from fungi and bacteria …

Bufadienolides from animal and plant sources

L Krenn, B Kopp - Phytochemistry, 1998 - Elsevier
BUFADIENOLIDES FROM ANIMAL AND PLANT SOURCES* Page 1 ~ Pergamon Plh
S0031-9422(97)00426-3 Phytochemt.~tr),, Vol. 48, No. I, pp. 1 29, 1998 (i 1998 Elsevier Science …

Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment

LJ Deng, Y Li, M Qi, JS Liu, S Wang, LJ Hu… - European journal of …, 2020 - Elsevier
Bufadienolides are cardioactive C24 steroids with an α-pyrone ring at position C17. In the
last ten years, accumulating studies have revealed the anticancer activities of …

Isolation and structure of five new cancer cell growth inhibitory bufadienolides from the Chinese traditional drug Ch'an Su

T Nogawa, Y Kamano, A Yamashita… - Journal of natural …, 2001 - ACS Publications
Five new bufadienolides, 3β-formyloxyresibufogenin (1), 19-oxobufalin (2), 19-
oxodesacetylcinobufagin (3), 6α-hydroxycinobufagin (4), and 1β-hydroxybufalin (5), have …

Bufadienolides of plant and animal origin

PS Steyn, FR Van Heerden - Natural product reports, 1998 - pubs.rsc.org
Bufadienolides of plant and animal origin Page 1 Bufadienolides of plant and animal origin
Pieter S. Steyn*,a and Fanie R. van Heerdenb aSASOL Centre for Chemistry, Potchefstroom …

Systematic screening and characterization of novel bufadienolides from toad skin using ultra‐performance liquid chromatography/electrospray ionization quadrupole …

Y Liu, Y Xiao, X Xue, X Zhang… - … Communications in Mass …, 2010 - Wiley Online Library
During the discovery process of novel compounds, it is of significant importance to
differentiate novel from known compounds in crude extracts before starting the time …

Structure–activity relationship analysis of bufadienolide-induced in vitro growth inhibitory effects on mouse and human cancer cells

L Moreno Y. Banuls, E Urban, M Gelbcke… - Journal of natural …, 2013 - ACS Publications
The in vitro growth inhibitory effects of 27 bufadienolides and eight degradation products,
with two cardenolides (ouabain and digoxin) chosen as reference compounds, were …

Biotransformation of bufadienolides by cell suspension cultures of Saussurea involucrata

X Zhang, M Ye, Y Dong, H Hu, S Tao, J Yin, D Guo - Phytochemistry, 2011 - Elsevier
The biotransformation of three bioactive bufadienolides, namely, bufotalin (1),
telocinobufagin (2), and gamabufotalin (3) by cell suspension cultures of Saussurea …

Simultaneous determination of three bufadienolides in rat plasma after intravenous administration of bufadienolides extract by ultra performance liquid …

Y Zhang, X Tang, X Liu, F Li, X Lin - Analytica chimica acta, 2008 - Elsevier
A novel, rapid and specific ultra performance liquid chromatography electrospray ionization
tandem mass spectrometry (UPLC-ESI-MS/MS) method has been developed for …

Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibition

LQ De Sousa, K da Conceição Machado… - Toxicon, 2017 - Elsevier
Amphibians present pharmacologically active aliphatic, aromatic and heterocyclic molecules
in their skin as defense against microorganisms, predators and infections, such as steroids …