Effects of genetics and sex on acute gene expression changes in the hippocampus following neonatal ethanol exposure in BXD recombinant inbred mouse strains

JA Baker, JT Brettin, MK Mulligan, KM Hamre - Brain Sciences, 2022 - mdpi.com
Fetal alcohol spectrum disorders (FASD) are prevalent neurodevelopmental disorders.
Genetics have been shown to have a role in the severity of alcohol's teratogenic effects on …

Effects of genetics and sex on adolescent behaviors following neonatal ethanol exposure in BXD recombinant inbred strains

JA Baker, MK Mulligan, KM Hamre - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Fetal alcohol spectrum disorders (FASD) are the leading preventable
neurodevelopmental disorders and two hallmark symptoms of FASD are abnormal behavior …

Genetic influences on the amount of cell death in the neural tube of BXD mice exposed to acute ethanol at midgestation

ET Théberge, JA Baker, C Dubose… - Alcoholism: Clinical …, 2019 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) have a strong genetic component
although the genes that underlie this are only beginning to be elucidated. In the present …

Molecular changes during neurodevelopment following second-trimester binge ethanol exposure in a mouse model of fetal alcohol spectrum disorder: from immediate …

K Mantha, BI Laufer, SM Singh - Developmental neuroscience, 2014 - karger.com
Fetal alcohol spectrum disorder (FASD) is an umbrella term that refers to a wide range of
behavioral and cognitive deficits resulting from prenatal alcohol exposure. It involves …

Molecular pathways underpinning ethanol-induced neurodegeneration

D Goldowitz, AA Lussier, JK Boyle, K Wong… - Frontiers in …, 2014 - frontiersin.org
While genetics impacts the type and severity of damage following developmental ethanol
exposure, little is currently known about the molecular pathways that mediate these effects …

Third trimester-equivalent ethanol exposure is characterized by an acute cellular stress response and an ontogenetic disruption of genes critical for synaptic …

ML Kleiber, BI Laufer, RL Stringer… - Developmental …, 2014 - karger.com
The developing brain is remarkably sensitive to alcohol exposure, resulting in the wide
range of cognitive and neurobehavioral characteristics categorized under the term fetal …

Binge-like prenatal ethanol exposure causes impaired cellular differentiation in the embryonic forebrain and synaptic and behavioral defects in adult mice

S Subbanna, BS Basavarajappa - Brain Sciences, 2022 - mdpi.com
An embryo's in-utero exposure to ethanol due to a mother's alcohol drinking results in a
range of deficits in the child that are collectively termed fetal alcohol spectrum disorders …

Effects of acute ethanol exposure on regulatory mechanisms of Bcl‐2‐associated apoptosis promoter, bad, in neonatal rat cerebellum: differential effects during …

KI Siler‐Marsiglio, I Madorsky, Q Pan… - Alcoholism: Clinical …, 2006 - Wiley Online Library
Background: Prenatal alcohol exposure produces anatomical and behavioral abnormalities
associated with fetal alcohol syndrome (FAS). Animal FAS models have demonstrated …

mRNA expression analysis of the hippocampus in a vervet monkey model of fetal alcohol spectrum disorder

RF Gillis, RM Palmour - Journal of Neurodevelopmental Disorders, 2022 - Springer
Background Fetal alcohol spectrum disorders (FASD) are common, yet preventable
developmental disorders that stem from prenatal exposure to alcohol. This exposure leads …

The ameliorative effects of choline on ethanol-induced cell death in the neural tube of susceptible BXD strains of mice

F Xu, JD Thomas, D Goldowitz… - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Fetal alcohol spectrum disorders (FASD) are the leading preventable cause of
intellectual disability, providing the impetus for evaluating various potential treatments to …