We have carried out functional and in vitro studies on a novel analog of neuropeptide Y
which shows selectivity for the prejunctional or neuropeptide YY 2 receptor. In anaesthetised …

Neuropeptide Y (NPY) is a potent inhibitor of neurotransmitter release through the Y2
receptor subtype. Specific antagonists for the Y2 receptors have not yet been described …

GR231118, BW1911U90, Bis (31/31′){[Cys31, Trp32, Nva34] neuropeptide Y (31–36)}(T-
190) and [Trp–Arg–Nva–Arg–Tyr] 2-NH2 (T-241) are peptide analogs of the C-terminus of …

In order to stabilize the C-terminal dodecapeptide of neuropeptide Y (NPY) we replaced
Leu28 and Thr32 by Lys and Glu, respectively, and subsequently linked these residues by …

Subtypes of the neuropeptide Y (NPY) receptor in the rat brain were identified by the use of
the selective Y-1 analog,[Leu 31-Pro 34] NPY. In rat brain homogenate binding studies,[Leu …

Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian brain
and acts in humans via at least three receptor subtypes: Y1, Y2, and Y5. Whereas selective …

Recently, we found abundant mRNA and binding sites for neuropeptide Y Y1-like receptors
in the human cerebral cortex. However, an earlier study using indirect labeling methods …

1 Neuropeptide Y (NPY) and peptide YY (PYY) act at receptors referred to as Y1 and Y2,
while the Y3 receptor is specific to NPY and does not recognize PYY. The effects of NPY, its …

Neuropeptide Y has potent appetite stimulating effects which are mediated by hypothalamic
receptors believed to be of the neuropeptide Y Y1 and/or neuropeptide Y Y5 subtype. In …

We have investigated binding and functional effects of a new peptide YY analogue,[Pro 34]
peptide YY, at Y 1 and Y 2-like subtypes of receptors for peptide YY and neuropeptide Y. In …