Oxysterols are cholesterol metabolites that can be produced through enzymatic or radical
processes. They constitute a large family of lipids (ie the oxysterome) involved in a plethora …

Oxysterols are structurally identical to cholesterol, but with one or more additional oxygen
containing functional groups (such as alcohol, carbonyl or epoxide groups). The wide array …

Oxygenated derivatives of cholesterol (oxysterols) present a remarkably diverse profile of
biological activities, including effects on sphingolipid metabolism, platelet aggregation …

Oxysterols have long been known for their important role in cholesterol homeostasis, where
they are involved in both transcriptional and posttranscriptional mechanisms for controlling …

Oxysterols are oxygenated derivatives of cholesterol that are intermediates or even end
products in cholesterol excretion pathways. Because of their ability to pass cell membranes …

Oxysterols are oxygenated forms of cholesterol generated via autooxidation by free radicals
and ROS, or formed enzymically by a variety of enzymes such as those involved in the …

Oxysterols are cholesterol metabolites now considered bona fide bioactive lipids. Recent
studies have identified new receptors for oxysterols involved in immune and inflammatory …

I have been involved in research on oxysterols since 1963 and this review is intended to
cover some of the most important aspects of this work. The first project dealed with 7α …

The present review aims to provide a complete and comprehensive summary of current
literature relevant to oxysterols and related diseases. Oxidation of cholesterol leads to the …

Oxysterols are the 27-carbon products of cholesterol oxidation by both enzymic and non-
enzymic mechanisms. Their roles in cholesterol homeostasis, as well as in diseases in …