A transdiagnostic review of neuroimaging studies of apathy and disinhibition in dementia
LM Jenkins, L Wang, H Rosen, S Weintraub - Brain, 2022 - academic.oup.com
Apathy and disinhibition are common and highly distressing neuropsychiatric symptoms
associated with negative outcomes in persons with dementia. This paper is a critical review …
associated with negative outcomes in persons with dementia. This paper is a critical review …
Disease-specific profiles of apathy in Alzheimer's disease and behavioural-variant frontotemporal dementia differ across the disease course
Apathy is one of the most prevalent and disabling non-cognitive symptoms of dementia. This
loss of motivation and pervasive decline in goal-directed behaviour represents a core …
loss of motivation and pervasive decline in goal-directed behaviour represents a core …
Apathy in Alzheimer's disease: A neurocircuitry based perspective
SF Mehak, AB Shivakumar, V Saraf… - Ageing Research …, 2023 - Elsevier
In addition to memory deficits and other cognitive disturbances, patients with Alzheimer's
disease (AD) experience neuropsychiatric symptoms, notably apathy, which is a state of …
disease (AD) experience neuropsychiatric symptoms, notably apathy, which is a state of …
Apathy associated with neurocognitive disorders: recent progress and future directions
Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …
[HTML][HTML] The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and …
DC Steffens, M Fahed, KJ Manning, L Wang - Translational psychiatry, 2022 - nature.com
Apathy is a common condition that involves diminished initiative, diminished interest and
diminished emotional expression or responsiveness. It is highly prevalent in the context of a …
diminished emotional expression or responsiveness. It is highly prevalent in the context of a …
Apathy: a neurocircuitry model based on frontotemporal dementia
S Ducharme, BH Price, BC Dickerson - Journal of Neurology …, 2018 - jnnp.bmj.com
Apathy is a symptom shared among many neurological and psychiatric disorders. However,
the underlying neurocircuitry remains incompletely understood. Apathy is one of the core …
the underlying neurocircuitry remains incompletely understood. Apathy is one of the core …
State of the science: apathy as a model for investigating behavioral and psychological symptoms in dementia
L Massimo, HC Kales… - Journal of the American …, 2018 - Wiley Online Library
Apathy is one of the most common and pervasive of the behavioral and psychological
symptoms of dementia (BPSDs). Apathy has profound consequences for morbidity, mortality …
symptoms of dementia (BPSDs). Apathy has profound consequences for morbidity, mortality …
The neuroimaging basis of apathy: Empirical findings and conceptual challenges
SE Starkstein, S Brockman - Neuropsychologia, 2018 - Elsevier
Apathy, usually defined as loss of motivation, is common in both neurodegenerative
conditions such as Alzheimer's disease, and acute neurological disorders such as stroke …
conditions such as Alzheimer's disease, and acute neurological disorders such as stroke …
Apathy in Alzheimer's disease and frontotemporal dementia: distinct clinical profiles and neural correlates
Objective Apathy is the most prevalent and disabling non-cognitive symptom of dementia
and affects 90% of patients across the disease course. Despite its pervasiveness, how …
and affects 90% of patients across the disease course. Despite its pervasiveness, how …
[HTML][HTML] Apathy as a treatment target in Alzheimer's disease: implications for clinical trials
Apathy is one of the most prevalent, stable and persistent neuropsychiatric symptom across
the neurocognitive disorders spectrum. Recent advances in understanding of …
the neurocognitive disorders spectrum. Recent advances in understanding of …