Nephrotic syndrome is characterized by urinary excretion of plasma proteases or
proteasuria. There is a lack of data on the quantity, activity status and identity of these …

Chronic kidney disease (CKD) is the gradual decrease in renal function. Currently available
biomarkers are effective only in detecting late stage CKD. Biomarkers of early stage CKD …

Background. Nephrotic syndrome is a condition that is clinically associated with poor
outcome. In this study, we compared different techniques of urine sample preparation in …

Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

Renal disorders account for a substantial fraction of the budget for health care in many
countries. Proteinuria is a frequent manifestation in afflicted patients, but the origin of the …

Mechanisms underlying the onset and progression of nephropathy in diabetic patients are
not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease …

Proteome analysis has emerged as a new field of protein science offering the possibility of
achieving unbiased identification, quantification and functional assessment of all proteins …

During the past few years, proteomics has been extensively applied to various fields of
medicine including nephrology. Current applications of renal and urinary proteomics are to …

Nephrotic syndrome is not a single disease; rather, it is a term for numerous diseases and
pathological types. Renal biopsy is of use in determining the diagnosis and prognosis, and …

Abstract Knowledge of the human genome has fertilized research in the embryonic field of
proteomics. The aim of this Review is to examine the recent application of emerging …