Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)

R Benedé-Ubieto, FJ Cubero, YA Nevzorova - Gut microbes, 2024 - Taylor & Francis
ABSTRACT Obesity, insulin resistance (IR), and the gut microbiome intricately interplay in
Metabolic-associated Steatotic Liver Disease (MASLD), previously known as Non-Alcoholic …

[HTML][HTML] Implication of gut microbiota in nonalcoholic fatty liver disease

J Boursier, AM Diehl - PLoS pathogens, 2015 - journals.plos.org
It is now well established that gut flora and chronic liver diseases are closely interrelated.
This association is most evident at late stages of the disease: cirrhosis and impaired liver …

[HTML][HTML] Understanding the role of the gut microbiome and microbial metabolites in non-alcoholic fatty liver disease: current evidence and perspectives

N Vallianou, GS Christodoulatos, I Karampela… - Biomolecules, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …

[HTML][HTML] The role of the gut-liver axis in metabolic dysfunction-associated fatty liver disease

R Martín-Mateos, A Albillos - Frontiers in immunology, 2021 - frontiersin.org
The complex interplay between the gut microbiota, the intestinal barrier, the immune system
and the liver is strongly influenced by environmental and genetic factors that can disrupt the …

[HTML][HTML] Non-alcoholic fatty liver and the gut microbiota

S Bashiardes, H Shapiro, S Rozin, O Shibolet… - Molecular …, 2016 - Elsevier
Background Non-alcoholic fatty liver (NAFLD) is a common, multi-factorial, and poorly
understood liver disease whose incidence is globally rising. NAFLD is generally …

[HTML][HTML] New Insights into the Pathogenesis of Metabolic-Associated Fatty Liver Disease (MAFLD): Gut–Liver–Heart Crosstalk

K Yang, M Song - Nutrients, 2023 - mdpi.com
Metabolism-associated fatty liver disease (MAFLD) is a multifaceted disease that involves
complex interactions between various organs, including the gut and heart. It is defined by …

Non-alcoholic steatohepatitis: a microbiota-driven disease

AR Moschen, S Kaser, H Tilg - Trends in Endocrinology & Metabolism, 2013 - cell.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as a major health problem
worldwide. Whereas overnutrition and obesity are crucially involved in the development of a …

The pathophysiology of MASLD: an immunometabolic perspective

J Schwärzler, F Grabherr, C Grander… - Expert review of …, 2024 - Taylor & Francis
Introduction Metabolic-associated liver diseases have emerged pandemically across the
globe and are clinically related to metabolic disorders such as obesity and type 2 diabetes …

[HTML][HTML] Gut dysfunction and non-alcoholic fatty liver disease

F Grabherr, C Grander, M Effenberger… - Frontiers in …, 2019 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) has emerged as one of the leading liver diseases
worldwide. NAFLD is characterized by hepatic steatosis and may progress to an …

Targeting gut-liver axis for the treatment of nonalcoholic steatohepatitis: translational and clinical evidence

A Federico, M Dallio, J Godos, C Loguercio… - Translational …, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is widely emerging as the most prevalent liver
disorder and is associated with increased risk of liver-related and cardiovascular mortality …