Identification of peptide and protein ligands for the caveolin-scaffolding domain: implications for the interaction of caveolin with caveolae-associated proteins

J Couet, S Li, T Okamoto, T Ikezu, MP Lisanti - Journal of Biological …, 1997 - ASBMB
Caveolin, a 21-24-kDa integral membrane protein, is a principal component of caveolae
membranes. We have suggested that caveolin functions as a scaffolding protein to organize …

The membrane-spanning domains of caveolins-1 and-2 mediate the formation of caveolin hetero-oligomers: Implications for the assembly of caveolae membranes in …

K Das, RY Lewis, PE Scherer, MP Lisanti - Journal of Biological Chemistry, 1999 - ASBMB
The mammalian caveolin gene family consists of caveolins-1,-2, and-3. The expression of
caveolin-3 is muscle-specific. In contrast, caveolins-1 and-2 are co-expressed, and they form …

Mutational analysis of the properties of caveolin-1: a novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions

KS Song, ZL Tang, S Li, MP Lisanti - Journal of Biological Chemistry, 1997 - ASBMB
Caveolin is a principal structural component of caveolae membranes in vivo Recently, a
family of caveolin-related proteins has been identified; caveolin has been retermed caveolin …

A role for the caveolin scaffolding domain in mediating the membrane attachment of caveolin-1: the caveolin scaffolding domain is both necessary and sufficient for …

A Schlegel, RB Schwab, PE Scherer… - Journal of Biological …, 1999 - ASBMB
Here, we have created a series of caveolin-1 (Cav-1) deletion mutants to examine whether
the membrane spanning segment is required for membrane attachment of caveolin-1 in vivo …

A molecular dissection of caveolin-1 membrane attachment and oligomerization: two separate regions of the caveolin-1 C-terminal domain mediate membrane …

A Schlegel, MP Lisanti - Journal of Biological Chemistry, 2000 - ASBMB
Caveolins form interlocking networks on the cytoplasmic face of caveolae. The
cytoplasmically directed N and C termini of caveolins are separated by a central …

Expression and Characterization of Recombinant Caveolin: PURIFICATION BY POLYHISTIDINE TAGGING AND CHOLESTEROL-DEPENDENT INCORPORATION …

S Li, KS Song, MP Lisanti - Journal of Biological Chemistry, 1996 - ASBMB
Caveolin, a 22-24-kDa integral membrane protein, is a principal component of caveolar
membranes in vivo. Caveolin has been proposed to function as a scaffolding protein to …

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

MP Lisanti, PE Scherer, ZL Tang, M Sargiacomo - Trends in cell biology, 1994 - Elsevier
Abstract Caveolae, 50–100 nm invaginations that represent a subcompartment of the
plasma membrane, have been known for many years, but their exact roles remain uncertain …

Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal …

PE Scherer, ZL Tang, M Chun, M Sargiacomo… - Journal of Biological …, 1995 - ASBMB
Caveolin, an integral membrane protein, is a principal component of caveolae membranes
in vivo. Two isoforms of caveolin have been identified: a slower migrating 24-kDa species (α …

Molecular characterization of caveolin association with the Golgi complex: identification of a cis-Golgi targeting domain in the caveolin molecule

R Luetterforst, E Stang, N Zorzi, A Carozzi… - The Journal of cell …, 1999 - rupress.org
Caveolins are integral membrane proteins which are a major component of caveolae. In
addition, caveolins have been proposed to cycle between intracellular compartments and …

Oligomeric structure of caveolin: implications for caveolae membrane organization.

M Sargiacomo, PE Scherer, ZL Tang… - Proceedings of the …, 1995 - National Acad Sciences
A 22-kDa protein, caveolin, is localized to the cytoplasmic surface of plasma membrane
specializations called caveolae. We have proposed that caveolin may function as a …