An update for mesenchymal stem cell therapy in lupus nephritis

W Li, W Chen, L Sun - Kidney Diseases, 2021 - karger.com
Background: Lupus nephritis (LN) is the most severe organ manifestations of systemic lupus
erythematosus (SLE). Although increased knowledge of the disease pathogenesis has …

[HTML][HTML] Efficacy of mesenchymal stem cells in animal models of lupus nephritis: a meta-analysis

T Zhou, C Liao, HY Li, W Lin, S Lin, H Zhong - Stem Cell Research & …, 2020 - Springer
Background Lupus nephritis is usually manifested by proteinuria, active urinary sediment,
hypertension, and renal failure and is a serious complication with more than 50 …

[HTML][HTML] Immunomodulatory activity of mesenchymal stem cells in lupus nephritis: Advances and applications

J Li, M Luo, B Li, Y Lou, Y Zhu, X Bai, B Sun… - Frontiers in …, 2022 - frontiersin.org
Lupus nephritis (LN) is a significant cause of various acute and chronic renal diseases,
which can eventually lead to end-stage renal disease. The pathogenic mechanisms of LN …

Therapeutic potential of allogeneic mesenchymal stromal cells transplantation for lupus nephritis

J Barbado, S Tabera, A Sánchez, J García-Sancho - Lupus, 2018 - journals.sagepub.com
Animal and human studies have suggested the potential of mesenchymal stromal cells
(MSCs) to treat systemic lupus erythematosus (SLE). Here, we present the results of …

Functional characteristics and application of mesenchymal stem cells in systemic lupus erythematosus

WY Tang, JH Liu, CJ Peng, Y Liao, JS Luo… - Archivum Immunologiae …, 2021 - Springer
Systemic lupus erythematosus (SLE) is a rare, heterogeneous autoimmune and
autoinflammatory disease that affects both sexes and all races, although this disease …

[HTML][HTML] Mesenchymal stem cells for the treatment of systemic lupus erythematosus: is the cure for connective tissue diseases within connective tissue?

FA Carrion, FE Figueroa - Stem cell research & therapy, 2011 - Springer
Mesenchymal stem cells (MSCs) are now known to display not only adult stem cell
multipotency but also robust anti-inflammatory and regenerative properties. After …

[HTML][HTML] Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis

A Thiel, G Yavanian, MD Nastke, P Morales… - Scientific reports, 2015 - nature.com
Adult tissue-derived mesenchymal stromal cells (MSCs) are showing promise in clinical
trials for systemic lupus erythematosus (SLE). However, the inability to manufacture large …

Mesenchymal stem cell transplantation in systemic lupus erythematous, a mesenchymal stem cell disorder

A Fathollahi, NB Gabalou, S Aslani - Lupus, 2018 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disorder
with involvement of several organs and systems such as the kidney, lung, brain and the …

Infusion of human bone marrow-derived mesenchymal stem cells alleviates autoimmune nephritis in a lupus model by suppressing follicular helper T-cell …

E Jang, M Jeong, S Kim, K Jang, BK Kang… - Cell …, 2016 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
production of autoantibodies to components of the cell nucleus. These autoantibodies are …

[HTML][HTML] Mesenchymal stem cell therapy: hope for patients with systemic lupus erythematosus

A Li, F Guo, Q Pan, S Chen, J Chen, H Liu… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Although previous
studies have demonstrated that SLE is related to the imbalance of cells in the immune …