Cardiac hypertrophy causes heart failure and is associated with hyperglycemia in patients
with diabetes mellitus. Mibefradil, which acts as a T-type calcium channel blocker, exerts …

Bawei Chenxiang Wan (BCW), a well-known traditional Chinese Tibetan medicine formula,
is effective for the treatment of acute and chronic cardiovascular diseases. In the present …

Purpose Schisandra is a well-known traditional Chinese medicine in East Asia. As a
traditional Chinese medicine derivative with Schisandra chinensis as raw material, bicyclol …

Background Trimetazidine, as an anti-ischemic and antioxidant agent, has been
demonstrated to have many cardioprotective effects. However, whether early administration …

Aims Resveratrol is a polyphenolic compound that has received much attention for its use in
ameliorating various systemic pathological conditions. The present study was performed to …

Baicalein is a natural flavonoid extracted from the root of Scutellaria baicalensis that exhibits
a variety of pharmacological activities. In this study, we investigated the molecular …

Ivabradine (Iva), a heart rate reducing agent that specifically inhibits the pacemaker I (f) ionic
current, has been demonstrated to be cardioprotective in many cardiovascular diseases …

Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage
in acute myocardial infarction, and its treatment remains a clinical challenge. Ginsenoside …

Heart failure (HF) is a clinical syndrome caused by impairment of ventricular filling, ejection
of blood, or both and is categorized as HF with reduced ejection fraction (HFrEF) or HF with …

Objectives This study aimed to evaluate berberine (BBR) effects on myocardial hypertrophy
(MH) and associated mechanisms. Methods BBR effects on MH were evaluated in rats with …