Application of the EIIP/ISM bioinformatics concept in development of new drugs

V Veljkovic, N Veljkovic, JA Esté… - Current medicinal …, 2007 - ingentaconnect.com
The development of a new therapeutic drug is a complex, lengthy and expensive process.
On average, only one out of 10,000-30,000 originally synthesized compounds will clear all …

Bioinformatics approaches for new drug discovery: a review

K Malathi, S Ramaiah - Biotechnology and Genetic Engineering …, 2018 - Taylor & Francis
Prolonged antibiotic therapy for the bacterial infections has resulted in high levels of
antibiotic resistance. Initially, bacteria are susceptible to the antibiotics, but can gradually …

[图书][B] Bioinformatics and drug discovery

RS Larson, TI Oprea - 2006 - Springer
A remarkable number of novel bioinformatics methods and techniques have become
available in recent years, enabling us to more rapidly identify new molecular and cellular …

Bioinformatics and drug discovery

P Murray-Rust - Current Opinion in Biotechnology, 1994 - Elsevier
Bioinformatics and drug discovery Page 1 Bioinformatics and drug discovery Peter Murray-Rust
Glaxo Research and Development, Greenford, UK Bioinformatics involves both the automatic …

[PDF][PDF] In-Silico Drug Design: A revolutionary approach to change the concept of current Drug Discovery Process

L Boruah, A Das, LM Nainwal, N Agarwal… - Indian Journal of …, 2013 - Citeseer
Computational methods play a central role in modern drug discovery process. It includes the
design and management of small molecule libraries, initial hit identification through virtual …

[PDF][PDF] Modern drug discovery process: An in silico approach

VS Rao, K Srinivas - Journal of bioinformatics and sequence …, 2011 - academicjournals.org
Drug discovery process is a critical issue in the pharmaceutical industry since it is a very cost-
effective and time consuming process to produce new drug potentials and enlarge the scope …

In silico methods and tools for drug discovery

B Shaker, S Ahmad, J Lee, C Jung, D Na - Computers in biology and …, 2021 - Elsevier
In the past, conventional drug discovery strategies have been successfully employed to
develop new drugs, but the process from lead identification to clinical trials takes more than …

Computer-aided drug designing

M Gore, NS Desai - Clinical Bioinformatics, 2014 - Springer
Computer-aided drug designing has emerged as a cost-effective and rapid tool for the
discovery of newer therapeutic agents. Several algorithms have been developed to analyze …

The evolving role of information technology in the drug discovery process

J Augen - Drug discovery today, 2002 - Elsevier
Information technologies for chemical structure prediction, heterogeneous database access,
pattern discovery, and systems and molecular modeling have evolved to become core …

[图书][B] Bioinformatics Tools for Pharmaceutical Drug Product Development

VP Chavda, K Anand, V Apostolopoulos - 2023 - books.google.com
BIOINFORMATICS TOOLS FOR Pharmaceutical DRUG PRODUCT DLEVELOPMENT A
timely book that details bioinformatics tools, artificial intelligence, machine learning …