The bioinformatics toolbox for circRNA discovery and analysis

L Chen, C Wang, H Sun, J Wang, Y Liang… - Briefings in …, 2021 - academic.oup.com
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …

Closing the circle: current state and perspectives of circular RNA databases

M Vromman, J Vandesompele… - Briefings in …, 2021 - academic.oup.com
Circular RNAs (circRNAs) are covalently closed RNA molecules that have been linked to
various diseases, including cancer. However, a precise function and working mechanism …

CircPro: an integrated tool for the identification of circRNAs with protein-coding potential

X Meng, Q Chen, P Zhang, M Chen - Bioinformatics, 2017 - academic.oup.com
Circular RNAs (circRNAs), a novel class of endogenous RNAs, are widespread in eukaryotic
cells. Emerging roles in diverse biological processes suggest that circRNA is a promising …

New insight into circRNAs: characterization, strategies, and biomedical applications

XY Feng, SX Zhu, KJ Pu, HJ Huang, YQ Chen… - … Hematology & Oncology, 2023 - Springer
Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …

Microarray is an efficient tool for circRNA profiling

S Li, S Teng, J Xu, G Su, Y Zhang, J Zhao… - Briefings in …, 2019 - academic.oup.com
Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory
noncoding RNAs in latest years. With the widespread application of RNA sequencing (RNA …

Advances in the identification of circular RNAs and research into circRNAs in human diseases

S Jiao, S Wu, S Huang, M Liu, B Gao - Frontiers in Genetics, 2021 - frontiersin.org
Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs (ncRNAs) with a
closed-loop structure that are mainly produced by variable processing of precursor mRNAs …

A comprehensive review of circRNA: from purification and identification to disease marker potential

S Xu, LY Zhou, M Ponnusamy, LX Zhang, YH Dong… - PeerJ, 2018 - peerj.com
Circular RNA (circRNA) is an endogenous noncoding RNA with a covalently closed cyclic
structure. Based on their components, circRNAs are divided into exonic circRNAs, intronic …

CIRCpedia v2: an updated database for comprehensive circular RNA annotation and expression comparison

R Dong, XK Ma, GW Li, L Yang - Genomics, Proteomics and …, 2018 - academic.oup.com
Circular RNAs (circRNAs) from back-splicing of exon (s) have been recently identified to be
broadly expressed in eukaryotes, in tissue-and species-specific manners. Although …

circMine: a comprehensive database to integrate, analyze and visualize human disease–related circRNA transcriptome

W Zhang, Y Liu, Z Min, G Liang, J Mo, Z Ju… - Nucleic Acids …, 2022 - academic.oup.com
Many circRNA transcriptome data were deposited in public resources, but these data show
great heterogeneity. Researchers without bioinformatics skills have difficulty in investigating …

CircFunBase: a database for functional circular RNAs

X Meng, D Hu, P Zhang, Q Chen, M Chen - Database, 2019 - academic.oup.com
Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes
and play important roles in diverse biological processes. However, a comprehensive …