Stomach cancer is the fifth most common cancer in terms of prevalence and incidence and
the fourth leading cause of mortality in men and women worldwide. It is well-established that …

Background Epigenetic alteration of gene expression is a common event in human cancer.
DNA methylation is a well-known epigenetic process, but verifying the exact nature of …

DNA methylation is an early event in tumorigenesis. Here, by integrative analysis of DNA
methylation and gene expression and utilizing machine learning approaches, we introduced …

Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence
and development are closely related to epigenetic modifications. Methylation of DNA before …

Abstract Oral Squamous Cell Carcinoma (OSCC) is a serious and one of the most common
and highly aggressive malignancies. Epigenetic factors such as DNA methylation have been …

Background We performed a genome-wide scan of 27,578 CpG loci covering 14,475 genes
to identify differentially methylated loci (DML) in colorectal carcinoma (CRC). Methods We …

Purpose: Metastasis is the leading cause of death for gastric carcinoma. An epigenetic
biomarker panel for predicting gastric carcinoma metastasis could have significant clinical …

Abnormal DNA methylation, an epigenetic modification, has increasingly been linked to the
pathogenesis of many human cancers. However, there has been little focus on the DNA …

Background Although primary (PGC) and remnant gastric cancers (RGC) both originate from
the same gastrointestinal organ, they have very distinct clinicopathological behaviors. We …

Background Accumulating evidence indicates aberrant DNA methylation is involved in
gastric tumourigenesis, suggesting it may be a useful clinical biomarker for the disease. The …