We compared the activity and physiologic effects of cardiac angiotensin converting enzyme
(ACE) using isovolumic hearts from male Wistar rats with left ventricular hypertrophy due to …

BACKGROUND The intracardiac conversion rate of angiotensin (Ang) I to Ang II and the
expression of angiotensin converting enzyme (ACE) mRNA are amplified in rat hearts with …

1. Chronic heart failure was induced in rats by ligation of the left coronary artery to produce a
left ventricular myocardial infarct. 2. Cardiac angiotensin-converting enzyme (ACE) was …

We have recently shown that the octapeptide angiotensin II is a potent stimulus of protein
synthesis and growth in cultured cardiomyocytes. The present study was performed to …

FlGUREl. LeR-daorBcm inananimd6 weeksafterinductknofexperimentdaor6c~. effects are
not the only determinants for regression of LV hypertrophy. Other factors such as …

BACKGROUND The degree of cardiac hypertrophy is not only load dependent: Among other
factors, the renin-angiotensin system may play a role in the regulation of cardiac myocyte …

BACKGROUND After myocardial infarction, the noninfarcted left ventricle develops reactive
hypertrophy associated with a depressed coronary flow reserve, myocardial interstitial …

In addition to the circulating renin-angiotensin system, recent data demonstrate the
existence of tissue renin-angiotensin systems that may be important in cardiovascular …

Reduced preload and afterload to the heart are important effects of angiotensin converting
enzyme (ACE) inhibitors in the treatment of congestive heart failure. However, since …

Background Cardiac volume overload by an aortocaval shunt increases left ventricular end-
diastolic pressure (LVEDP) and plasma and cardiac renin activity and results in LV …