Repurposing chlorpromazine to treat COVID-19: The reCoVery study

M Plaze, D Attali, AC Petit, M Blatzer, E Simon-Loriere… - L'encephale, 2020 - Elsevier
Objectives The ongoing COVID-19 pandemic has caused approximately 2,350,000
infections worldwide and killed more than 160,000 individuals. In Sainte-Anne Hospital …

The large action of chlorpromazine: translational and transdisciplinary considerations in the face of COVID-19

E Stip, TA Rizvi, F Mustafa, S Javaid… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome (SARS) in
humans that is caused by SARS-associated coronavirus type 2 (SARS-CoV-2). In the …

Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine

M Plaze, D Attali, M Prot, AC Petit, M Blatzer… - International journal of …, 2021 - Elsevier
Introduction Urgent action is needed to fight the ongoing coronavirus disease 2019 (COVID-
19) pandemic by reducing the number of infected cases, contagiousness and severity …

Overview of the potential use of fluvoxamine for COVID-19 and long COVID

K Hashimoto - Discover Mental Health, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has presented a serious worldwide threat to
public health since its emergence in late 2019. From a safety point of view, drug repurposing …

Observational study of chlorpromazine in hospitalized patients with COVID-19

N Hoertel, M Sanchez-Rico, R Vernet, AS Jannot… - Clinical drug …, 2021 - Springer
Introduction Chlorpromazine has been suggested as being potentially useful in patients with
coronavirus disease 2019 (COVID-19) on the grounds of its potential antiviral and anti …

[HTML][HTML] Part II. High-dose methotrexate with leucovorin rescue for severe COVID-19: an immune stabilization strategy for SARS-CoV-2 induced 'PANIC'attack

EM Frohman, NR Villemarette-Pittman, RA Cruz… - Journal of the …, 2020 - Elsevier
Here, in Part II of a duology on the characterization and potential treatment for COVID-19, we
characterize the application of an innovative treatment regimen for the prevention of the …

Drug repurposing of selective serotonin reuptake inhibitors: Could these drugs help fight COVID-19 and save lives?

Y Pashaei - Journal of Clinical Neuroscience, 2021 - Elsevier
The current 2019 novel coronavirus disease (COVID-19), an emerging infectious disease, is
undoubtedly the most challenging pandemic in the 21st century. A total of 92,977,768 …

[HTML][HTML] Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine shows antiviral activity against the novel variants in vitro

SM Fred, S Kuivanen, H Ugurlu… - Frontiers in …, 2022 - frontiersin.org
Repurposing of currently available drugs is a valuable strategy to tackle the consequences
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …

<? covid19?> Management of clozapine treatment during the COVID-19 pandemic

S Gee, F Gaughran, J MacCabe… - Therapeutic …, 2020 - journals.sagepub.com
Clozapine is the only available treatment for refractory schizophrenia but its use involves
frequent physical contact with healthcare workers for the purpose of mandatory blood …

Mechanisms of action of fluvoxamine for COVID-19: a historical review

Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …