Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccine
Although there have been no cases of serotype 2 wild poliovirus for more than 20 years,
transmission of serotype 2 vaccine-derived poliovirus (VDPV2) and associated paralytic …
transmission of serotype 2 vaccine-derived poliovirus (VDPV2) and associated paralytic …
Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two …
I De Coster, I Leroux-Roels, AS Bandyopadhyay… - The Lancet, 2021 - thelancet.com
Background Two novel type 2 oral poliovirus vaccine (OPV2) candidates, novel OPV2-c1
and novel OPV2-c2, designed to be more genetically stable than the licensed Sabin …
and novel OPV2-c2, designed to be more genetically stable than the licensed Sabin …
Type 2 poliovirus detection after global withdrawal of trivalent oral vaccine
IM Blake, M Pons-Salort, NA Molodecky… - … England Journal of …, 2018 - Mass Medical Soc
Background Mass campaigns with oral poliovirus vaccine (OPV) have brought the world
close to the eradication of wild poliovirus. However, to complete eradication, OPV must itself …
close to the eradication of wild poliovirus. However, to complete eradication, OPV must itself …
Poliovirus vaccination options for achieving eradication and securing the endgame
CF Estívariz, MA Pallansch, A Anand… - Current opinion in …, 2013 - Elsevier
Highlights•2012 had the lowest number of polio cases in the lowest number of
countries.•Outbreaks of vaccine-derived poliovirus have increased and are mostly due to …
countries.•Outbreaks of vaccine-derived poliovirus have increased and are mostly due to …
Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants …
X Sáez-Llorens, AS Bandyopadhyay, C Gast… - The Lancet, 2021 - thelancet.com
Background Continued emergence and spread of circulating vaccine-derived type 2
polioviruses and vaccine-associated paralytic poliomyelitis from Sabin oral poliovirus …
polioviruses and vaccine-associated paralytic poliomyelitis from Sabin oral poliovirus …
[HTML][HTML] Update on vaccine-derived poliovirus outbreaks—worldwide, January 2020–June 2021
MM Alleman - MMWR. Morbidity and mortality weekly report, 2021 - cdc.gov
During January 2020–June 2021, 44 cVDPV outbreaks were ongoing, resulting in 1,335
paralytic cases; 38 (86%) were cVDPV type 2 (cVDPV2). Initial use of novel type 2 oral …
paralytic cases; 38 (86%) were cVDPV type 2 (cVDPV2). Initial use of novel type 2 oral …
Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3
MT Yeh, M Smith, S Carlyle, JL Konopka-Anstadt… - Nature, 2023 - nature.com
Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …
Emergence of vaccine-derived poliovirus in high-income settings in the absence of oral polio vaccine use
M Hill, AS Bandyopadhyay, AJ Pollard - The Lancet, 2022 - thelancet.com
Comment 714 www. thelancet. com Vol 400 September 3, 2022 risk of vaccine-associated
paralytic poliomyelitis caused by Sabin 2. 6 Although most countries eliminated Sabinlike …
paralytic poliomyelitis caused by Sabin 2. 6 Although most countries eliminated Sabinlike …
Risk factors for the spread of vaccine-derived type 2 polioviruses after global withdrawal of trivalent oral poliovirus vaccine and the effects of outbreak responses with …
LV Cooper, AS Bandyopadhyay, N Gumede… - The Lancet Infectious …, 2022 - thelancet.com
Background Expanding outbreaks of circulating vaccine-derived type 2 poliovirus (cVDPV2)
across Africa after the global withdrawal of trivalent oral poliovirus vaccine (OPV) in 2016 …
across Africa after the global withdrawal of trivalent oral poliovirus vaccine (OPV) in 2016 …
The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 …
P Van Damme, I De Coster, AS Bandyopadhyay… - The Lancet, 2019 - thelancet.com
Background Use of oral live-attenuated polio vaccines (OPV), and injected inactivated polio
vaccines (IPV) has almost achieved global eradication of wild polio viruses. To address the …
vaccines (IPV) has almost achieved global eradication of wild polio viruses. To address the …