Molecular physiology of vertebrate Na+/H+ exchangers

S Wakabayashi, M Shigekawa… - Physiological …, 1997 - journals.physiology.org
This review describes recent progress concerning the molecular aspects of the Na+/H+
exchanger. The Na+/H+ exchanger is an important regulator for intracellular pH, cell volume …

Mammalian Na+/H+ exchanger gene family: structure and function studies

CH Yun, CM Tse, SK Nath, SA Levine… - American Journal …, 1995 - journals.physiology.org
Na+/H+ exchangers are integral plasma membrane proteins that exchange extracellular
Na+ for intracellular H+ with a stoichiometry of one for one. They are inhibitable by the …

Physiological role and regulation of the Na+/H+ exchanger

ME Malo, L Fliegel - Canadian journal of physiology and …, 2006 - cdnsciencepub.com
In mammalian eukaryotic cells, the Na+/H+ exchanger is a family of membrane proteins that
regulates ions fluxes across membranes. Plasma membrane isoforms of this protein extrude …

Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms

J Noel, J Pouyssegur - American Journal of Physiology-Cell …, 1995 - journals.physiology.org
Since the cloning of the first member of the Na+/H+ exchanger (NHE) family, termed NHE1,
four NHE isoforms have been cloned (NHE2, NHE3, NHE4, and the trout beta-NHE) and …

[HTML][HTML] The expanding family of eucaryotic Na+/H+ exchangers

L Counillon, J Pouysségur - Journal of Biological Chemistry, 2000 - ASBMB
Maintaining intracellular pH values close to neutrality is a crucial task for a wide variety of
cells. Hence, various mechanisms for pH regulation have been selected early in evolution …

Na+/H+ Exchangers

J Orlowski, S Grinstein - Comprehensive Physiology, 2011 - Wiley Online Library
Tightly coupled exchange of Na+ for H+ occurs across the surface membrane of virtually all
living cells. For years, the underlying molecular entity was unknown and the full …

Multiple Modes of Regulation of Na+/H+ Exchangers

H Hayashi, K Szászi, S Grinstein - … of the New York Academy of …, 2002 - Wiley Online Library
Mammalian Na+/H+ exchangers (NHE) mediate electroneutral countertransport of H+ for
Na+ across the plasmalemmal and organellar membranes. They contribute to cellular and …

Structure and function of the NHE1 isoform of the Na+/H+ exchanger

E Slepkov, L Fliegel - Biochemistry and cell biology, 2002 - cdnsciencepub.com
The Na+/H+ exchanger is a ubiquitous, integral membrane protein involved in pH
regulation. It removes intracellular acid, exchanging a proton for an extracellular sodium ion …

Structure/function studies of the epithelial isoforms of the mammalian Na+/H+ exchanger gene family

M Tse, S Levine, C Yun, S Brant, LT Counillon… - The Journal of …, 1993 - Springer
Na+/H+ exchangers or antiporters are plasma membrane transport proteins, which in
eukaryotes exchange extracellular Na+ for intracellular H+ with a stoichiometry of 1: 1 [31 …

Structural and functional analysis of the Na+/H+ exchanger

ER Slepkov, JK Rainey, BD Sykes… - Biochemical …, 2007 - portlandpress.com
The mammalian NHE (Na+/H+ exchanger) is a ubiquitously expressed integral membrane
protein that regulates intracellular pH by removing a proton in exchange for an extracellular …