Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Cisplatin, an inorganic complex of platinum, is a chemotherapeutic drug that has been used
for 45 years. Despite the progress of pharmaceutical sciences and medicine and the …

Cisplatin is one of the most widely-used drugs to treat cancers. However, its nephrotoxic and
ototoxic side-effects remain major clinical limitations. Recent studies have improved our …

Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Cisplatin is a chemotherapeutic drug widely used against a variety of cancers. Its clinical
utility is severely limited by its toxicity, which mainly affects, but is not limited to, the inner ear …

Cis-diamminedichloridoplatinum (II)(cisplatin) is a chemotherapeutic drug currently
prescribed for the treatment of many types of human cancer, but its use is associated with …

Context Cisplatin, a coordination platinum complex, is used as a potential anti-neoplastic
agent, having well recognized DNA-damaging property that triggers cell-cycle arrest and cell …

The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …

Cisplatin (cis-diamminedichloroplatinum (II)) is an effective chemotherapeutic agent, and is
successfully used in the treatment of a wide range of tumors. Despite its effectiveness as an …

Cisplatin (cis-diamminedichloroplatinum (II)) is the oldest known chemotherapeutic agent.
Since the identification of its anti-tumour activity, it earned a remarkable place as a treatment …