Adverse health effects of betel quid and the risk of oral and pharyngeal cancers

PH Chen, Q Mahmood, GL Mariottini… - BioMed research …, 2017 - Wiley Online Library
Global reports estimate 600 million betel quid (BQ) chewers. BQ chewing has been
demonstrated not only to be a risk factor for cancers of the oral cavity and pharynx and oral …

Betel quid–associated cancer: Prevention strategies and targeted treatment

AMS Ko, CH Lee, YC Ko - Cancer letters, 2020 - Elsevier
Betel quid (BQ) and areca nut use are at risk of cancer. This review includes the latest
evidence of carcinogenesis caused by BQ exposure, suggests possible prevention …

How each component of betel quid is involved in oral carcinogenesis: mutual interactions and synergistic effects with other carcinogens—a review article

S Islam, M Muthumala, H Matsuoka, O Uehara… - Current oncology …, 2019 - Springer
Abstract Purpose of Review The roles of the components of betel quid in oral carcinogenesis
remain unclear. The purpose of the present review is to highlight the effect of each …

Betel quid chewing and the risk of oral and oropharyngeal cancers: a meta‐analysis with implications for cancer control

N Guha, S Warnakulasuriya… - … journal of cancer, 2014 - Wiley Online Library
We conducted a random‐effects meta‐analysis of 50 publications assessing the relationship
between oral/oropharyngeal cancer and chewing betel quid, with (BQ+ T) or without added …

Betel quid chewing without tobacco: a meta-analysis of carcinogenic and precarcinogenic effects

H Song, Y Wan, YY Xu - Asia Pacific Journal of Public …, 2015 - journals.sagepub.com
Betel quid without tobacco is an important factor influencing the incidences of oral cancer
and precancer. This study systematically evaluated the associations between betel quid …

Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking

CP Wen, MK Tsai, WSI Chung, HL Hsu… - Cancer causes & …, 2010 - Springer
Objectives This cohort study is to assess the extent of cancer risks of betel quid chewing
(without tobacco added) beyond oral cancer, as such information was limited from case …

A comprehensive analysis on the association between tobacco-free betel quid and risk of head and neck cancer in Taiwanese men

YH Wu, CJ Yen, JR Hsiao, CY Ou, JS Huang… - PloS one, 2016 - journals.plos.org
Objectives Although betel quid (BQ) is an established risk factor of head and neck cancer
(HNC), insufficiencies exist in the literature regarding the dose-response, BQ types, HNC …

Association of betel nut with carcinogenesis: revisit with a clinical perspective

RN Sharan, R Mehrotra, Y Choudhury, K Asotra - 2012 - journals.plos.org
Betel nut (BN), betel quid (BQ) and products derived from them are widely used as a socially
endorsed masticatory product. The addictive nature of BN/BQ has resulted in its widespread …

Chewing betel quid and the risk of metabolic disease, cardiovascular disease, and all-cause mortality: a meta-analysis

T Yamada, K Hara, T Kadowaki - PloS one, 2013 - journals.plos.org
Background Betel nut (Areca nut) is the fruit of the Areca catechu tree. Approximately 700
million individuals regularly chew betel nut (or betel quid) worldwide and it is a known risk …

Mutational signatures and mutagenic impacts associated with betel quid chewing in oral squamous cell carcinoma

SC Su, LC Chang, CW Lin, MK Chen, CP Yu… - Human genetics, 2019 - Springer
Betel quid (BQ) chewing is a prevailing risk for oral squamous cell carcinoma (OSCC) in
Southeast Asia. Yet, the detailed mechanisms by which BQ chewing damages the genome …