Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone

A Ortiz, R Alcázar Arroyo… - Expert Review of …, 2023 - Taylor & Francis
Introduction Patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) are at
high risk of CKD progression and cardiovascular events. Despite treatment with renin …

Hyperkalemia risk with finerenone: results from the FIDELIO-DKD trial

R Agarwal, A Joseph, SD Anker… - Journal of the …, 2022 - journals.lww.com
Background Finerenone reduced risk of cardiorenal outcomes in patients with CKD and type
2 diabetes in the FIDELIO-DKD trial. We report incidences and risk factors for hyperkalemia …

Cardiorenal benefits of finerenone: protecting kidney and heart

JR González-Juanatey, JL Górriz, A Ortiz… - Annals of …, 2023 - Taylor & Francis
Persons with diabetes and chronic kidney disease (CKD) have a high residual risk of
developing cardiovascular (CV) complications despite treatment with renin-angiotensin …

Potassium management with finerenone: Practical aspects

C Wanner, P Fioretto, CP Kovesdy… - Endocrinology …, 2022 - Wiley Online Library
Introduction Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has
favourable effects on cardiorenal outcomes in patients with mild‐to‐severe chronic kidney …

[PDF][PDF] Role of finerenone in the treatment of diabetic kidney disease: patient selection and clinical perspectives

A Shaikh, J Ray, KN Campbell - Therapeutics and Clinical Risk …, 2022 - Taylor & Francis
Diabetes is the leading cause of chronic and end stage kidney disease globally. Despite
recent advances in therapies for diabetic kidney disease (DKD), there remains a critical …

Finerenone: a novel mineralocorticoid receptor antagonist for cardiorenal protection in CKD and T2DM

A Long, M Salvo - Annals of Pharmacotherapy, 2022 - journals.sagepub.com
Objective: To describe the pharmacology, clinical and safety evidence, and relevance to
clinical practice of finerenone. Data Sources: A literature search was conducted utilizing …

Efficacy and safety of finerenone for treatment of diabetic kidney disease: current knowledge and future perspective

V Marzolla, M Infante, A Armani, M Rizzo… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Diabetic kidney disease (DKD) represents a leading cause of morbidity and
mortality in subjects with diabetes and develops in more than one third of diabetic patients …

The cardiovascular outcomes of finerenone in patients with chronic kidney disease and type 2 diabetes: A meta-analysis of randomized clinical trials

B Abdelazeem, MA Elbadawy, AK Awad… - Intractable & Rare …, 2022 - jstage.jst.go.jp
Recently, a few randomized control trials (RCTs) suggested that finerenone has been shown
to reduce cardiovascular events in patients with CKD and DM-2. We aimed to analyze the …

Finerenone: a new mineralocorticoid receptor antagonist to beat chronic kidney disease

R Raj - Current Opinion in Nephrology and Hypertension, 2022 - journals.lww.com
The nonsteroidal MRA finerenone could improve renal and cardiac outcomes further in
diabetics with kidney disease when added to renin-angiotensin system inhibitors …

Pharmacotherapy considerations with finerenone in the treatment of chronic kidney disease associated with type 2 diabetes

E Ashjian, M Clarke, K Pogue - American Journal of Health …, 2023 - academic.oup.com
Purpose This review provides an overview of the management of chronic kidney disease
(CKD) associated with type 2 diabetes (T2D), how the novel treatment class of nonsteroidal …