Bad players in AL amyloidosis in the current era of treatment

N Kreiniz, MA Gertz - Expert review of hematology, 2023 - Taylor & Francis
ABSTRACT Introduction Systemic AL amyloidosis (ALA) is a clonal plasma cell (PC) disease
characterized by deposition of amyloid fibrils in different organs and tissues. Traditionally …

[引用][C] Prognosis and risk assessment in AL amyloidosis–There and back again

E Kastritis, MA Dimopoulos - British Journal of Haematology, 2017 - Wiley Online Library
The presentation and course of AL amyloidosis is characterized by significant heterogeneity,
depending on the organ tropism of the amyloidogenic light chain, the severity of organ …

A comprehensive overview of AL amyloidosis disease characteristics accumulated over two decades at a single referral center in Korea

SE Yoon, D Kim, J Choi, JH Min, BJ Kim, JS Kim… - International Journal of …, 2023 - Springer
Background Characteristics of AL amyloidosis across Asia are not well-described in the
literature. Thus, we overviewed the incidence and disease characteristics of AL amyloidosis …

[HTML][HTML] Systemic AL Amyloidosis and Precision Medicine

A Rüfer, R Schwotzer - healthbook …, 2021 - onco-hema.healthbooktimes.org
In amyloid light-chain (AL) amyloidosis, a small plasma-cell clone, or less frequently a
mature B-cell clone, produces toxic monoclonal light chains that can be deposited in the …

Updates in the diagnosis and management of AL amyloidosis

J Cook, E Muchtar, R Warsame - Current Hematologic Malignancy Reports, 2020 - Springer
Abstract Purpose of Review Light chain (AL) amyloidosis is an insidious progressive
disease which results in significant morbidity and inevitable mortality if not diagnosed and …

[HTML][HTML] Systemic AL amyloidosis: current approach and future direction

MB Zerdan, L Nasr, F Khalid, S Allam, Y Bouferraa… - Oncotarget, 2023 - ncbi.nlm.nih.gov
Systemic Light chain (AL) amyloidosis is a monoclonal plasma cell proliferative disorder
characterized by deposition of amyloidogenic monoclonal light chain fragments causing …

Comprehensive review of AL amyloidosis: some practical recommendations

R Al Hamed, AH Bazarbachi, A Bazarbachi… - Blood Cancer …, 2021 - nature.com
Amyloid light chain (AL) amyloidosis is among the more common and more severe of the
amyloidoses usually involving the slow proliferation of a bone-marrow-residing plasma cell …

[HTML][HTML] Improved survival in AL amyloidosis: a population-based study on 1,430 patients diagnosed in Sweden 1995-2013

BM Weiss, SH Lund, M Bjorkholm, AD Cohen… - Blood, 2016 - Elsevier
Introduction: AL amyloidosis (AL) is a plasma cell disorder characterized by life-threatening
vital organ dysfunction resulting in nearly a third of patients dying within the first year of …

A European collaborative study of cyclophosphamide, bortezomib, and dexamethasone in upfront treatment of systemic AL amyloidosis

G Palladini, S Sachchithanantham… - Blood, The Journal …, 2015 - ashpublications.org
The combination of cyclophosphamide/bortezomib/dexamethasone (CyBorD) showed early
promise of high rates of hematologic responses tempered by studies showing the inability to …

[PDF][PDF] Defying the Odds: 30 Years in AL Amyloidosis Research, Recent Barriers to Clinical Trial Enrollment

V Sanchorawala, B Barroso, AC Shelton… - Blood …, 2024 - ashpublications.org
Author contributions and disclosures: VS designed the study, performed data analysis, and
wrote manuscript. BB, EG and AS collected the data. LM, TJ, NB, AS, JMS, and VS …