Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

As outlined in the accompanying Minireviews, autophagy is a complicated and highly
regulated process that delivers cellular material to lysosomes for degrading, recycling, and …

Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation,
development, and homeostasis. Autophagy principally serves an adaptive role to protect …

Autophagy (“self-eating”) constitutes one of the most spectacular yet subtly regulated
phenomena in cell biology. Similarly to cell division, differentiation, and death, autophagy is …

Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …

Autophagy degrades the cytoplasmic contents engulfed by autophagosomes. Besides
providing energy and building blocks during starvation via random degradation, autophagy …

The relentless efforts of thousands of researchers have allowed deciphering the molecular
machinery that regulates and executes autophagy, thus identifying multiple molecular …

Autophagy is a process in which intracellular components and dysfunctional organelles are
delivered to the lysosome for degradation and recycling. Autophagy has various …

Autophagy is a catabolic trafficking pathway for bulk destruction and turnover of long-lived
proteins and organelles via regulated lysosomal degradation. In eukaryotic cells, autophagy …

Autophagy was originally described as a highly conserved system for the degradation of
cytosol through a lysosome-dependent pathway. In response to starvation, autophagy …