Neurodegeneration in inflammatory conditions in the central nervous system follows a basic
pathway, mediated by pro-inflammatory cytokines and macrophage and microglia activation …

A precise and dynamic immune response is pivotal for maintaining defense against
pathogens, cellular homeostasis, and tissue repair following injury. Dysregulated immune …

Neurodegenerative and neuropsychological disorders are becoming a greater proportion of
the global disease burden; however the pathogenic mechanisms by which these disorders …

Aberrant innate and adaptive immune responses are neurodegenerative disease effectors.
Disease is heralded by a generalized, but subtle immune activation orchestrated by the …

Neurodegeneration in multiple sclerosis (MS) is the structural correlate of permanent
neurological disability in patients. The histopathological features of neurodegeneration …

There is an increasing recognition that inflammation plays a critical role in
neurodegenerative diseases of the CNS, including Alzheimer's disease, amyotrophic lateral …

Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic …

Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease that impacts
mostly the central nervous system (CNS). It has been classically classified as a T cell …

Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …

Chronic inflammation is characterized by longstanding microglial activation followed by
sustained release of inflammatory mediators, which aid in enhanced nitrosative and …