Flavonoids have many positive pharmacological properties, such as antioxidant, antitumor,
and anti-inflammatory activities. However, factors such as low water solubility and low …

The aim of the study was to investigate the potential of nanocrystals to enhance the oral
bioavailability of apigenin (AP), a bioactive flavonoid with various pharmacological activities …

The present work aimed to apply the liquid antisolvent precipitation (LAP) method for
preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability …

The purpose of this paper is to prepare a stable apigenin nanosuspension with a drug
concentration of 1.11 mg/mL through green and efficient antisolvent method. Compared with …

The particle size and distribution have a significant impact on the bioavailability and stability
of insoluble drugs. A scale-up microreactor system based on an ellipsoidal baffle mixer was …

ARTcrystal®-technology is a novel technique for a more efficient production of nanocrystals.
It consists of a high speed stirring (HSS) step as pre-milling and subsequent high pressure …

Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor
bioavailability upon oral administration. Hence, the objective of this research work was to …

The main aim of this study was to modify the supercritical antisolvent precipitation method to
enhance the mass transfer in order to prepare smaller nanoparticles of drugs. The …

In this study, a novel carbon nanopowder (CNP) drug carrier was developed to improve the
oral bioavailability of apigenin (AP). Solid dispersions (SDs) of AP with CNP were prepared …

Apigenin (Apig) is used as a model drug due to its many beneficial bio-activities and
therapeutic potentials. Nevertheless, its poor water solubility and low storage stability have …