Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease
M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …
complex risk structure thought to be influenced by interactions between genetic variants and …
Effect modification between genes and environment and Parkinson's disease risk
MT Periñán, K Brolin, S Bandres‐Ciga… - Annals of …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a complex neurodegenerative condition in which genetic and
environmental factors interact to contribute to its etiology. Remarkable progress has been …
environmental factors interact to contribute to its etiology. Remarkable progress has been …
Gene–environment interactions: key to unraveling the mystery of Parkinson's disease
HM Gao, JS Hong - Progress in neurobiology, 2011 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease. The
gradual, irreversible loss of dopamine neurons in the substantia nigra is the signature lesion …
gradual, irreversible loss of dopamine neurons in the substantia nigra is the signature lesion …
Environmental impact on the epigenetic mechanisms underlying Parkinson's disease pathogenesis: a narrative review
Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …
unclear etiology and no disease-modifying treatment to date. PD is considered a …
Gene–environment interactions in Parkinson's disease: Specific evidence in humans and mammalian models
JR Cannon, JT Greenamyre - Neurobiology of disease, 2013 - Elsevier
Interactions between genetic factors and environmental exposures are thought to be major
contributors to the etiology of Parkinson's disease. While such interactions are poorly …
contributors to the etiology of Parkinson's disease. While such interactions are poorly …
Genetic profile, environmental exposure, and their interaction in Parkinson's disease
The discovery of causative mutations for Parkinson's disease (PD) as well as their functional
characterization in cellular and animal models has provided crucial insight into the …
characterization in cellular and animal models has provided crucial insight into the …
Mechanisms of gene-environment interactions in Parkinson's disease
SM Fleming - Current environmental health reports, 2017 - Springer
Abstract Purpose of Review The purpose of the study was to discuss the main mechanisms
associated with environmental and genetic factors that contribute to the development of …
associated with environmental and genetic factors that contribute to the development of …
Gene–environment interactions in Parkinson's disease
CA Ross, WW Smith - Parkinsonism & related disorders, 2007 - Elsevier
PD is the second most common neurodegenerative disease, and affects 5% of the
population by the age of 85. PD is a multi-factorial disease with a complex etiology including …
population by the age of 85. PD is a multi-factorial disease with a complex etiology including …
Gene–environment interactions in Parkinson's disease: the importance of animal modeling
MP Horowitz, JT Greenamyre - Clinical Pharmacology & …, 2010 - Wiley Online Library
Parkinson's disease (PD), a late‐onset neurodegenerative disorder, occurs most commonly
in a “sporadic”(idiopathic) form, without a clearly defined genetic basis and only a vaguely …
in a “sporadic”(idiopathic) form, without a clearly defined genetic basis and only a vaguely …
Environmental toxins and Parkinson's disease
SM Goldman - Annual review of pharmacology and toxicology, 2014 - annualreviews.org
Parkinson's disease (PD) is a chronic, progressive, disabling neurodegenerative disorder
that begins in mid to late life and is characterized by motor impairment, autonomic …
that begins in mid to late life and is characterized by motor impairment, autonomic …
相关搜索
- parkinson's disease environment interactions
- epigenetic mechanisms risk factors
- disease mechanisms epigenetic landscape
- epigenetic mechanisms environmental impact
- parkinson's disease risk factors
- environmental exposure genetic profile
- disease mechanisms therapeutic modalities
- parkinson's disease genetic profile
- epigenetic mechanisms parkinson's disease
- parkinson's disease gene environment
- parkinson's disease environmental exposure
- parkinson's disease environmental toxins
- parkinson's disease epigenetic landscape