Enzymes are able to perform reactions under mild conditions, eg, pH and temperature, with
remarkable chemo-, regio-, and stereoselectivity. Because of this feature, the number of …

Enzymes are able to perform reactions under mild conditions, eg, pH and temperature, with
remarkable chemo-, regio-, and stereoselectivity. Due to this feature the number of …

Chiral secondary alcohols play an important role in pharmaceutical, agrochemical, and
chemical industries. In recent years, impressive steps forward have been achieved towards …

Over the past two years the application of ketoreductases in the commercial synthesis of
chiral alcohols has undergone a revolution. Biocatalysts are now often the preferred catalyst …

The use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated
enzymes, in the highly enantiospecific reduction of prochiral ketones is reviewed. The …

The development of cell‐free and self‐sufficient biocatalytic systems represents an
emerging approach to address more complex synthetic schemes under nonphysiological …

Herein we review recent advances in the asymmetric reduction of ketones by biocatalysts.
Included are discussions on recent developments in methodologies to control …

The enantioselective reduction of carbonyl groups is of interest for the production of various
chiral compounds such as hydroxy acids, amino acids, hydroxy esters, or alcohols. Such …

Chiral alcohols are useful intermediates for many pharmaceuticals and chemicals.
Enzymatic asymmetric reduction of prochiral carbonyl compounds is a promising method for …

The development of efficient syntheses for enantiomerically enriched α-hydroxy ketones is
an important research focus in the pharmaceutical industry. For example, α-hydroxy ketones …